Astrocytes play a pivotal role in maintaining the central nervous system (CNS) homeostasis
and function. In response to CNS injuries and diseases, reactive astrocytes are triggered. By …

With the development of human society, haze has become an important form of air pollution.
Haze is a mixture of fog and haze, and the main component of haze is fine particulate matter …

Overweight and obesity are now considered a worldwide pandemic and a growing public
health problem with severe economic and social consequences. Adipose tissue is an organ …

Schizophrenia is a chronic mental illness of unknown etiology. A growing and compelling
body of evidence implicates immunologic dysfunction as the key element in its …

Physical activity has been found to aid the maintenance of health in the elderly. Exercise-
induced skeletal muscle contractions lead to the production and secretion of many small …

Microglia are the resident immune cells of the central nervous system contributing
substantially to health and disease. There is increasing evidence that inflammatory microglia …

Hypothalamic interleukin-6 (IL6) exerts a broad metabolic control. Here, we demonstrated
that IL6 activates the ERK1/2 pathway in the ventromedial hypothalamus (VMH), stimulating …

Simple Summary This study identifies the molecular mechanisms through which BQ323636.
1 can enhance IL-6 and IL-6R expression, which leads to the activation of STAT3 and the …

Microglia, the intrinsic neuroimmune cells residing in the central nervous system (CNS),
exert a pivotal influence on brain development, homeostasis, and functionality …

In December 2019, a new viral disease emerged and quickly spread all around the world. In
March 2020, the COVID-19 outbreak was classified as a global pandemic and by June …