Although the primary control of gonadotropin secretion is by the hypothalamic GnRH and the
gonadal function is controlled by the pituitary gonadotropins and prolactin, the emerging …

Transcription factors and signaling pathways that regulate stem cells and specialized
hormone-producing cells in the pituitary gland have been the subject of intense study and …

The mechanisms that mediate plasticity in pituitary function have long been a subject of
vigorous investigation. Early studies overcame technical barriers and challenged conceptual …

It is well-established that anterior pituitary contains multiple endocrine cell populations, and
each of them can secrete one/two hormone (s) to regulate vital physiological processes of …

Through unique receptors, growth hormone (GH) stimulates ovarian follicles and Leydig
cells, working alone or synergistically with luteinizing hormone (LH) and follicle-stimulating …

The vertebrate pituitary is a dynamic organ, capable of adapting its hormone secretion to
different physiological demands. In this context, endocrinologists have debated for the past …

The Pou domain transcription factor Pit-1 is required for lineage determination and cellular
commitment processes during mammalian adenohypophysis development. Here we report …

The influence of 17α-methyltestosterone (MT) on growth responses, biological parameters
and the expression of genes involved in the GH–IGF pathway of the hypothalamic–pituitary …

The central circadian pacemaker in the suprachiasmatic nucleus (SCN) is a critical
component of the neuroendocrine circuit controlling gonadotropin secretion from the …

Sustained stimulation of G-protein-coupled receptors (GPCRs) typically causes receptor
desensitisation, which is mediated by phosphorylation, often within the C-terminal tail of the …