Astrocyte function from information processing to cognition and cognitive impairment
Astrocytes serve important roles that affect recruitment and function of neurons at the local
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
and network levels. Here we review the contributions of astrocyte signaling to synaptic …
Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
[HTML][HTML] Specialized astrocytes mediate glutamatergic gliotransmission in the CNS
Multimodal astrocyte–neuron communications govern brain circuitry assembly and function.
For example, through rapid glutamate release, astrocytes can control excitability, plasticity …
For example, through rapid glutamate release, astrocytes can control excitability, plasticity …
[HTML][HTML] Astrocytic activation generates de novo neuronal potentiation and memory enhancement
Astrocytes respond to neuronal activity and were shown to be necessary for plasticity and
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
memory. To test whether astrocytic activity is also sufficient to generate synaptic potentiation …
Astrocyte calcium signaling: the third wave
N Bazargani, D Attwell - Nature neuroscience, 2016 - nature.com
The discovery that transient elevations of calcium concentration occur in astrocytes, and
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
release'gliotransmitters' which act on neurons and vascular smooth muscle, led to the idea …
Diversity and specificity of astrocyte–neuron communication
CA Durkee, A Araque - Neuroscience, 2019 - Elsevier
Astrocytes are emerging as important players in synaptic function, and, consequently, on
brain function and animal behavior. According to the Tripartite Synapse concept, astrocytes …
brain function and animal behavior. According to the Tripartite Synapse concept, astrocytes …
[HTML][HTML] Gliotransmitters travel in time and space
The identification of the presence of active signaling between astrocytes and neurons in a
process termed gliotransmission has caused a paradigm shift in our thinking about brain …
process termed gliotransmission has caused a paradigm shift in our thinking about brain …
G-protein-coupled receptors in astrocyte–neuron communication
Astrocytes, a major type of glial cell, are known to play key supportive roles in brain function,
contributing to ion and neurotransmitter homeostasis, maintaining the blood–brain barrier …
contributing to ion and neurotransmitter homeostasis, maintaining the blood–brain barrier …
Ca2+ signaling in astrocytes from Ip3r2−/− mice in brain slices and during startle responses in vivo
R Srinivasan, BS Huang, S Venugopal… - Nature …, 2015 - nature.com
Intracellular Ca2+ signaling is considered to be important for multiple astrocyte functions in
neural circuits. However, mice devoid of inositol triphosphate type 2 receptors (IP3R2) …
neural circuits. However, mice devoid of inositol triphosphate type 2 receptors (IP3R2) …
[HTML][HTML] Calcium imaging reveals glial involvement in transcranial direct current stimulation-induced plasticity in mouse brain
Transcranical direct current stimulation (tDCS) is a treatment known to ameliorate various
neurological conditions and enhance memory and cognition in humans. tDCS has gained …
neurological conditions and enhance memory and cognition in humans. tDCS has gained …