Advancing the understanding of the tablet disintegration phenomenon–an update on recent studies
Disintegration is the de-aggregation of particles within tablets upon exposure to aqueous
fluids. Being an essential step in the bioavailability cascade, disintegration is a fundamental …
fluids. Being an essential step in the bioavailability cascade, disintegration is a fundamental …
Exploring the performance-controlling tablet disintegration mechanisms for direct compression formulations
N Maclean, E Walsh, M Soundaranathan… - International Journal of …, 2021 - Elsevier
The design and manufacture of tablets is a challenging process due to the complex
interrelationships between raw material properties, the manufacturing settings and the tablet …
interrelationships between raw material properties, the manufacturing settings and the tablet …
Hyperlipidemia control using the innovative association of lupin proteins and chitosan and α-cyclodextrin dietary fibers: food supplement formulation, molecular …
E Elmowafy, L Pavoni, DR Perinelli, M Tiboni… - … Food Research and …, 2022 - Springer
A dietary supplement potentially employed for the treatment and/or prevention of
hyperlipidemia was developed. The proposed product is composed of a combination of …
hyperlipidemia was developed. The proposed product is composed of a combination of …
[HTML][HTML] The impact of lactose type on disintegration: An integral study on porosity and polymorphism
PHM Janssen, A Berardi, JH Kok, AW Thornton… - European Journal of …, 2022 - Elsevier
Besides factors such as disintegrant and lubricant, the raw material properties of filler
excipients can have an impact on the disintegration behavior of a tablet. The current …
excipients can have an impact on the disintegration behavior of a tablet. The current …
Disintegrant selection in hydrophobic tablet formulations
S Bauhuber, G Warnke, A Berardi - Journal of Pharmaceutical Sciences, 2021 - Elsevier
The hydrophobicity of poorly soluble drugs can delay tablets disintegration. We probed here
the influence of different disintegrants on the disintegration of challenging hydrophobic …
the influence of different disintegrants on the disintegration of challenging hydrophobic …
[HTML][HTML] Application of co-processed excipients for developing fast disintegrating tablets: A review
The introduction of tablet dosage forms has brought a revolution in the pharmaceutical drug
delivery system. Different forms of tablets have been developed based on the target site, the …
delivery system. Different forms of tablets have been developed based on the target site, the …
Alginates as tablet disintegrants: Understanding disintegration mechanisms and defining ranges of applications
Alginates are biopolymers that have been investigated for their use in food and medical
fields. Minimal information is available regarding their potential application as tablet …
fields. Minimal information is available regarding their potential application as tablet …
Innovative method for longer effective corrosion inhibition time: controlled release oil palm empty fruit bunch hemicellulose inhibitor tablet
This study aims to develop a controlled release oil palm empty fruit bunch hemicellulose
(EFB-H) inhibitor tablet for mild steel in 1 M HCl. As plant extracts tend to deteriorate at …
(EFB-H) inhibitor tablet for mild steel in 1 M HCl. As plant extracts tend to deteriorate at …
Temperature: an overlooked factor in tablet disintegration
Disintegration is the first event in the bioavailability cascade after the ingestion of immediate
release tablets. Although the influence of various physico-chemical parameters of media on …
release tablets. Although the influence of various physico-chemical parameters of media on …
Formulation and in vitro evaluation of pellets containing sulfasalazine and caffeine to verify ileo-colonic drug delivery
A Broesder, SY Bircan, AB De Waard, AC Eissens… - Pharmaceutics, 2021 - mdpi.com
The ColoPulse coating is a pH-dependent coating that can be used to target drug release to
the ileo-colonic region. ColoPulse coated tablets and capsules have demonstrated their …
the ileo-colonic region. ColoPulse coated tablets and capsules have demonstrated their …