Phytosterols and triterpenoids for prevention and treatment of metabolic-related liver diseases and hepatocellular carcinoma

I Sánchez-Crisóstomo… - Current …, 2019 - ingentaconnect.com
Background: Liver ailments are among the leading causes of death; they originate from viral
infections, chronic alcoholism, and autoimmune illnesses, which may chronically be …

Technologies for solubility, dissolution and permeation enhancement of natural compounds

M Alshamrani, MK Khan, BA Khan, A Salawi… - Pharmaceuticals, 2022 - mdpi.com
The current review is based on the advancements in the field of natural therapeutic agents
which could be utilized for a variety of biomedical applications and against various diseases …

Terpenoids with antifungal activity trigger mitochondrial dysfunction in Saccharomyces cerevisiae

E Haque, S Irfan, M Kamil, S Sheikh, A Hasan… - Microbiology, 2016 - Springer
A number of pathogenic fungi like Candida, cannot survive upon damage to mitochondrial
DNA (mtDNA) while the budding yeast can tolerate the damage therefore we chose …

Amelioration of oxidative stress mediated inflammation and apoptosis in pancreatic islets by Lupeol in STZ-induced hyperglycaemic mice

AK Das, U Hossain, S Ghosh, S Biswas, M Mandal… - Life Sciences, 2022 - Elsevier
Abstract Background Type 1 Diabetes mellitus initiates by loss of pancreatic activity which
affects other major organs leading to multi-organ failure. Lupeol, a novel phytochemical, is …

[PDF][PDF] Lupeol isolated from Betula alnoides ameliorates amyloid beta induced neuronal damage via targeting various pathological events and alteration in …

M Kaundal, M Akhtar, R Deshmukh - J. Neurol. Neurosci, 2017 - academia.edu
Lupeol, a natural active constituent of Betula alnoides (BA), is well known for its anti-
inflammatory, anti-oxidant and neuroprotective activities. In present study the therapeutic …

Anti-diabetic potentials of Sorbaria tomentosa Lindl. Rehder: Phytochemistry (GC-MS analysis), α-amylase, α-glucosidase inhibitory, in vivo hypoglycemic, and …

F Naz, M Zahoor, M Ayaz, M Ashraf, A Nawaz… - Open …, 2023 - degruyter.com
This study aimed to examine the anti-diabetic effects of an unexplored medical plant
Sorbaria tomentosa Lindl. Rehder using in vitro and in vivo approaches. The extracts were …

Natural bioactive molecules with antidiabetic attributes: insights into structure–activity relationships

K Bhaskarachary, AKR Joshi - Studies in natural products chemistry, 2018 - Elsevier
Diabetes is a constellation of metabolic abnormalities, primarily characterized by impaired
glucose homeostasis and hyperglycemia. The disorder is underlined by complex …

Characterization of bioactive compounds from Ficus vallis-choudae Delile (Moraceae)

JJK Bankeu, A Dawé, M Mbiantcha… - Trends in …, 2017 - tpr.shahrood.iau.ir
Ficus vallis-choudae Delile has been reported to exhibit antifungal, anticonvulsant, anti-
inflammatory and antinociceptive activities. Herein we report the first ever …

A new antibacterial lupane ester from the seeds of Acokanthera oppositifolia Lam.

AM El Sayed, SM Ezzat, OM Sabry - Natural product research, 2016 - Taylor & Francis
As a part of ongoing investigation of Acokanthera oppositifolia (Lam.) Codd., four
compounds were isolated from its seeds, a new compound; lup-20 (29)-en-3 β-O-(3′-β …

[HTML][HTML] Hepatoprotective effects of nonpolar extracts from inflorescences of thistles Cirsium vulgare and Cirsium ehrenbergii on acute liver damage in rat

E Fernández-Martínez, M Jiménez-Santana… - Pharmacognosy …, 2017 - ncbi.nlm.nih.gov
Background: Drugs for the treatment of liver diseases are scarce and not effective enough.
Some species of the genus Cirsium possess hepatoprotective activity. There are no studies …