P-type ATPases: Many more enigmas left to solve

M Palmgren - Journal of Biological Chemistry, 2023 - ASBMB
P-type ATPases constitute a large ancient super-family of primary active pumps that have
diverse substrate specificities ranging from H+ to phospholipids. The significance of these …

Fast-forward on P-type ATPases: recent advances on structure and function

C Stock, T Heger, S Basse Hansen… - Biochemical Society …, 2023 - portlandpress.com
P-type ATPase are present in nearly all organisms. They maintain electrochemical gradients
for many solutes, in particular ions, they control membrane lipid asymmetry, and are crucial …

Investigation of the role of TmMYB16/123 and their targets (TmMTP1/11) in the tolerance of Taxus media to cadmium

S Feng, K Hou, H Zhang, C Chen, J Huang… - Tree …, 2023 - academic.oup.com
The toxicity and stress caused by heavy metal contamination has become an important
constraint to the growth and flourishing of trees. In particular, species belonging to the genus …

Structural basis of ion uptake in copper-transporting P1B-type ATPases

N Salustros, C Grønberg, NS Abeyrathna, P Lyu… - Nature …, 2022 - nature.com
Copper is essential for living cells, yet toxic at elevated concentrations. Class 1B P-type
(P1B-) ATPases are present in all kingdoms of life, facilitating cellular export of transition …

Genome-Wide Identification and Expression Profiling of Heavy Metal ATPase (HMA) Genes in Peanut: Potential Roles in Heavy Metal Transport

J Li, Z Zhang, G Shi - International Journal of Molecular Sciences, 2024 - mdpi.com
The heavy metal ATPase (HMA) family belongs to the P-type ATPase superfamily and plays
an essential role in the regulation of metal homeostasis in plants. However, the gene family …

Plastic recognition and electrogenic uniport translocation of 1 st-, 2 nd-, and 3 rd-row transition and post-transition metals by primary-active transmembrane P 1B-2 …

SS Abeyrathna, NS Abeyrathna, P Basak… - Chemical …, 2023 - pubs.rsc.org
Transmembrane P1B-type ATPase pumps catalyze the extrusion of transition metal ions
across cellular lipid membranes to maintain essential cellular metal homeostasis and …

Determining the effects of regulatory parameters on the structural dynamics of P-type ATPase membrane transporters

F Orädd - 2024 - diva-portal.org
Proteins are macromolecular machines with roles in all cellular activities and structures. The
functional properties of each protein is the result of its combination of 3D-structure and …

[PDF][PDF] Biochemical and Biophysical Characterization of Bacterial Transition Metal Transporters by Functional Reconstitution in Artificial Lipid Bilayers

NS Abeyrathna - 2022 - utd-ir.tdl.org
Transition metals play a vital role in all living organisms due to their key structural and
functional properties central to diverse metabolic processes. However, because of their high …