[HTML][HTML] Pharmacological therapeutics targeting RNA-dependent RNA polymerase, proteinase and spike protein: from mechanistic studies to clinical trials for COVID …

J Huang, W Song, H Huang, Q Sun - Journal of clinical medicine, 2020 - mdpi.com
An outbreak of novel coronavirus-related pneumonia COVID-19, that was identified in
December 2019, has expanded rapidly, with cases now confirmed in more than 211 …

Macrophage apoptosis and efferocytosis in the pathogenesis of atherosclerosis

MRF Linton, VR Babaev, J Huang, EF Linton… - Circulation …, 2016 - jstage.jst.go.jp
Macrophage apoptosis and the ability of macrophages to clean up dead cells, a process
called efferocytosis, are crucial determinants of atherosclerosis lesion progression and …

[HTML][HTML] Tissue factor-enriched neutrophil extracellular traps promote immunothrombosis and disease progression in sepsis-induced lung injury

H Zhang, Y Zhou, M Qu, Y Yu, Z Chen, S Zhu… - Frontiers in cellular …, 2021 - frontiersin.org
Background Patients with sepsis may progress to acute respiratory distress syndrome
(ARDS). Evidence of neutrophil extracellular traps (NETs) in sepsis-induced lung injury has …

[HTML][HTML] The role of potential oxidative biomarkers in the prognosis of acute ischemic stroke and the exploration of antioxidants as possible preventive and treatment …

FZ Kamal, R Lefter, H Jaber, IM Balmus… - International Journal of …, 2023 - mdpi.com
Ischemic strokes occur when the blood supply to a part of the brain is interrupted or reduced
due to arterial blockage, and it often leads to damage to brain cells or death. According to a …

Recent trends in electrochemical sensors for vital biomedical markers using hybrid nanostructured materials

KK Reddy, H Bandal, M Satyanarayana… - Advanced …, 2020 - Wiley Online Library
This work provides a succinct insight into the recent developments in electrochemical
quantification of vital biomedical markers using hybrid metallic composite nanostructures …

[HTML][HTML] Oleic acid exhibits an expressive anti-inflammatory effect in croton oil-induced irritant contact dermatitis without the occurrence of toxicological effects in mice

NS Pegoraro, C Camponogara, L Cruz… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Cutaneous inflammatory diseases, such as irritant contact
dermatitis, are usually treated with topical corticosteroids, which cause systemic and local …

An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo

C Wang, E Keliher, MWG Zeller… - Proceedings of the …, 2019 - National Acad Sciences
Myeloperoxidase (MPO) is a critical proinflammatory enzyme implicated in cardiovascular,
neurological, and rheumatological diseases. Emerging therapies targeting inflammation …

[HTML][HTML] Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: a new paradigm for drug discovery

J Huang, D Wang, LH Huang, H Huang - International journal of …, 2020 - mdpi.com
Epidemiological results revealed that there is an inverse correlation between high-density
lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease …

[HTML][HTML] Nε-carboxymethyl-lysine-induced PI3K/Akt signaling inhibition promotes foam cell apoptosis and atherosclerosis progression

Z Wang, Z Bao, Y Ding, S Xu, R Du, J Yan, L Li… - Biomedicine & …, 2019 - Elsevier
Advanced glycation end products (AGEs) are closely associated with diabetic
macrovascular complications. The present study aimed to investigate the effects of Nε …

Target-induced site-specific cleavage of phosphorothioate-modified hairpin DNA for amplified and label-free sensitive electrochemical myeloperoxidase assay

X Song, Y Liu, B Jiang, R Yuan, Y Xiang - Sensors and Actuators B …, 2023 - Elsevier
Abnormal myeloperoxidase (MPO) expression is associated with inflammation and
neurodegenerative diseases. By using a new phosphorothioate (PT)-modified DNA hairpin …