Medicine in the early twenty-first century: paradigm and anticipation-EPMA position paper 2016

O Golubnitschaja, B Baban, G Boniolo, W Wang… - EPMA Journal, 2016 - Springer
Background Challenges of “standardisation” and “individualisation” have always been
characteristic for medical services. In terms of individualisation, the best possible individual …

Tear fluid biomarkers in ocular and systemic disease: potential use for predictive, preventive and personalised medicine

S Hagan, E Martin, A Enríquez-de-Salamanca - Epma Journal, 2016 - Springer
In the field of predictive, preventive and personalised medicine, researchers are keen to
identify novel and reliable ways to predict and diagnose disease, as well as to monitor …

Flavonoids as an effective sensitizer for anti-cancer therapy: Insights into multi-faceted mechanisms and applicability towards individualized patient profiles

A Liskova, M Samec, L Koklesova, A Brockmueller… - Epma Journal, 2021 - Springer
Cost-efficacy of currently applied treatments is an issue in overall cancer management
challenging healthcare and causing tremendous economic burden to societies around the …

MAP kinase signalling pathways in cancer

AS Dhillon, S Hagan, O Rath, W Kolch - Oncogene, 2007 - nature.com
Cancer can be perceived as a disease of communication between and within cells. The
aberrations are pleiotropic, but mitogen-activated protein kinase (MAPK) pathways feature …

The crucial role of multiomic approach in cancer research and clinically relevant outcomes

M Lu, X Zhan - EPMA Journal, 2018 - Springer
Cancer with heavily economic and social burden is the hot point in the field of medical
research. Some remarkable achievements have been made; however, the exact …

Flavonoids against the Warburg phenotype—Concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism

M Samec, A Liskova, L Koklesova, SM Samuel, K Zhai… - Epma Journal, 2020 - Springer
The Warburg effect is characterised by increased glucose uptake and lactate secretion in
cancer cells resulting from metabolic transformation in tumour tissue. The corresponding …

Identification of clinical trait–related lncRNA and mRNA biomarkers with weighted gene co-expression network analysis as useful tool for personalized medicine in …

N Li, X Zhan - EPMA Journal, 2019 - Springer
Relevance The pathogenesis and biomarkers of ovarian cancer (OC) remain not well-known
in diagnosis, effective therapy, and prognostic assessment in OC personalized medicine …

Metal–organic framework-based biosensing platforms for the sensitive determination of trace elements and heavy metals: a comprehensive review

H Sohrabi, S Ghasemzadeh, S Shakib… - Industrial & …, 2022 - ACS Publications
Heavy metals in food and water sources are potentially harmful to humans. Determination of
these pollutants is critical for improving safety. Effective recognition systems are a …

An examination of colorectal cancer burden by socioeconomic status: evidence from GLOBOCAN 2018

R Sharma - EPMA journal, 2020 - Springer
Aim and background Colon and rectum (colorectal) cancer cause substantial mortality and
morbidity worldwide. The management and control of a complex disease such as cancer …

Specific properties of probiotic strains: relevance and benefits for the host

RV Bubnov, LP Babenko, LM Lazarenko, VV Mokrozub… - EPMA Journal, 2018 - Springer
Background Probiotics have tremendous potential to develop healthy diets, treatment, and
prevention. Investigation of in vitro cultural properties of health-promoting microorganisms …