Population management using gene drive: molecular design, models of spread dynamics and assessment of ecological risks

NO Rode, A Estoup, D Bourguet… - Conservation …, 2019 - Springer
CRISPR gene drive has recently been proposed as a promising technology for population
management, including in conservation genetics. The technique would consist in releasing …

Conserving New Zealand's native fauna: a review of tools being developed for the Predator Free 2050 programme

EC Murphy, JC Russell, KG Broome, GJ Ryan… - Journal of …, 2019 - Springer
The endemic fauna of New Zealand evolved in the absence of mammalian predators and
the introduction of the latter has been devastating. There have been numerous avian …

[PDF][PDF] Gene editing and agrifood systems

C Gao, EM Kikulwe, J Kuzma, M Lema, P Lidder… - 2022 - cgspace.cgiar.org
Gene-editing technologies represent a promising new tool for plant and animal breeding in
low-and middle-income countries. They enhance precision and efficiency over current …

MGDrivE 2: A simulation framework for gene drive systems incorporating seasonality and epidemiological dynamics

SL Wu, JB Bennett, HM Sánchez C… - PLoS computational …, 2021 - journals.plos.org
Interest in gene drive technology has continued to grow as promising new drive systems
have been developed in the lab and discussions are moving towards implementing field …

Rodent gene drives for conservation: opportunities and data needs

J Godwin, M Serr… - … of the Royal …, 2019 - royalsocietypublishing.org
Invasive rodents impact biodiversity, human health and food security worldwide. The
biodiversity impacts are particularly significant on islands, which are the primary sites of …

Gene drive: progress and prospects

N Wedell, TAR Price… - Proceedings of the …, 2019 - royalsocietypublishing.org
Gene drive is a naturally occurring phenomenon in which selfish genetic elements
manipulate gametogenesis and reproduction to increase their own transmission to the next …

Gene drive dynamics in natural populations: The importance of density dependence, space, and sex

S Dhole, AL Lloyd, F Gould - Annual review of ecology …, 2020 - annualreviews.org
The spread of synthetic gene drives is often discussed in the context of panmictic
populations connected by gene flow and described with simple deterministic models. Under …

Gene drives for vertebrate pest control: Realistic spatial modelling of eradication probabilities and times for island mouse populations

A Birand, P Cassey, JV Ross, JC Russell… - Molecular …, 2022 - Wiley Online Library
Invasive alien species continue to threaten global biodiversity. CRISPR‐based gene drives,
which can theoretically spread through populations despite imparting a fitness cost, could be …

Safe CRISPR: challenges and possible solutions

M Pineda, A Lear, JP Collins, S Kiani - Trends in biotechnology, 2019 - cell.com
Applications of CRISPR in human health and in gene drives are at the forefront of biological
research as tools. This technology will affect humankind and our environment, so as this …

Technological innovations enhance invasive species management in the Anthropocene

RM Fricke, JD Olden - BioScience, 2023 - academic.oup.com
Curbing the introduction, spread, and impact of invasive species remains a longstanding
management and policy prerogative. In recent decades, globalization and environmental …