Hypertensive heart disease constitutes functional and structural dysfunction and
pathogenesis occurring primarily in the left ventricle, the left atrium and the coronary arteries …

Elevated pro-inflammatory biomarkers and cytokines are associated with morbidity and
mortality in heart failure (HF). Preclinical and clinical studies have shown multiple …

Aging is associated with an increased risk of cardiovascular disease and death. Here we
show that oral supplementation of the natural polyamine spermidine extends the lifespan of …

Abstract Purpose of Review Heart failure with preserved ejection fraction (HFpEF) is a
relatively new disease entity used in medical terminology; however, both the number of …

Heart failure with preserved ejection fraction (HFpEF) is a growing public health concern,
with rising incidence alongside high morbidity and mortality. However, the pathophysiology …

Cardiac magnetic resonance (CMR) is emerging as an important tool in the assessment of
heart failure with preserved ejection fraction (HFpEF). This study sought to investigate the …

The clinical importance of heart failure with preserved ejection fraction (HFpEF) has recently
become apparent. HFpEF refers to heart failure (HF) symptoms with normal or near-normal …

Background and ethnopharmacological relevance: The morbidity and mortality of
cardiovascular diseases (CVDs) are among the highest of all diseases, necessitating the …

Uraemic Cardiomyopathy (UC) is recognised as an intricate and multifactorial disease which
portends a significant burden in patients with End-Stage Renal Disease (ESRD). The …

Aims Concentric hypertrophy following pressure-overload is linked to preserved systolic
function but impaired diastolic function, and is an important substrate for heart failure with …