Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …

▪ Abstract Macrophages express a broad range of plasma membrane receptors that mediate
their interactions with natural and altered-self components of the host as well as a range of …

We elucidated the molecular cross-talk between cartilage and synovium in osteoarthritis, the
most widespread arthritis in the world, using the powerful tool of single-cell RNA …

Macrophages (Mf) are a heterogeneous population of tissue-resident professional
phagocytes and a major component of the leukocyte infiltrate at sites of inflammation …

Myeloid cells in the tumor microenvironment (TME) can exist in immunosuppressive and
immunostimulatory states that impede or promote antitumor immunity, respectively. Blocking …

Septic shock, the most severe complication of sepsis, is a deadly disease. In recent years,
exciting advances have been made in the understanding of its pathophysiology and …

There is current evidence to demonstrate a close association between fungal sensitisation
and asthma severity. Whether such an association is causal remains to be confirmed, but …

Triggering receptors expressed by myeloid cells (TREMs) belong to a rapidly expanding
family of receptors that include activating and inhibitory isoforms encoded by a gene cluster …

The pulmonary endothelium is a highly regulated organ that performs a wide range of
functions under physiological and pathological conditions. Since endothelial dysfunction …

Multiple sclerosis (MS) is a chronic inflammatory neurodegenerative disease of the central
nervous system (CNS). The early stage is characterized by relapses and the later stage, by …