The ocular lens has a very high content of the antioxidant glutathione (GSH) and the
enzymes that can recycle its oxidized form, glutathione disulfide (GSSG), for further use. It …

Lutein (L) and zeaxanthin (Z) are dietary carotenoids derived from dark green leafy
vegetables, orange and yellow fruits that form the macular pigment of the human eyes. It was …

We previously quantified frailty in aged mice with frailty index (FI) that used specialized
equipment to measure health parameters. Here we developed a simplified, noninvasive …

Due to the implementation of the Montreal Protocol, which has limited, and is now probably
reversing, the depletion of the stratospheric ozone layer, only modest increases in solar UV …

Background Existing studies suggest that dietary vitamins and carotenoids might be
associated with a reduced risk of age-related cataract (ARC), although a quantitative …

Despite being a treatable disease, cataract is still the leading cause for blindness in the
world. Solar ultraviolet radiation is epidemiologically linked to cataract development, while …

Objectives The search for anticataract drugs has been continuing for decades; some
treatments no longer exist but antioxidants are still of much interest. Key findings The …

The human body harbors within it an intricate and delicate balance between oxidants and
antioxidants. Any disruption in this checks‐and‐balances system can lead to harmful …

Monday, February 13, 2017 167a aggregation phenomena. Amorphous aggregation of the g-
crystallins in the eye lens causes a widespread disease of aging, cataract. We combined …

Cataracts are one of the most prevalent diseases of the lens, affecting its transparency and
are the leading cause of reversible blindness in the world. The clarity of the lens is essential …