Circulating biomarkers for gliomas

M Westphal, K Lamszus - Nature Reviews Neurology, 2015 - nature.com
Currently, gliomas are diagnosed by neuroimaging, and refined diagnosis requires
resection or biopsy to obtain tumour tissue for histopathological classification and grading …

Recent insights into the microRNA-dependent modulation of gliomas from pathogenesis to diagnosis and treatment

A Mafi, A Rahmati, Z Babaei Aghdam, R Salami… - Cellular & Molecular …, 2022 - Springer
Gliomas are the most lethal primary brain tumors in adults. These highly invasive tumors
have poor 5-year survival for patients. Gliomas are principally characterized by rapid …

A multimodal deep neural network for human breast cancer prognosis prediction by integrating multi-dimensional data

D Sun, M Wang, A Li - IEEE/ACM transactions on …, 2018 - ieeexplore.ieee.org
Breast cancer is a highly aggressive type of cancer with very low median survival. Accurate
prognosis prediction of breast cancer can spare a significant number of patients from …

Bioinformatic profiling identifies an immune-related risk signature for glioblastoma

W Cheng, X Ren, C Zhang, J Cai, Y Liu, S Han, A Wu - Neurology, 2016 - AAN Enterprises
Objective: To investigate the local immune status and its prognostic value in glioma.
Methods: A cohort of 297 glioma samples with whole genome microarray expression data …

[HTML][HTML] MicroRNAs as prognostic markers and therapeutic targets in gliomas

A Sufianov, S Begliarzade, T Ilyasova, Y Liang… - Non-coding RNA …, 2022 - Elsevier
Gliomas are invasive brain tumors characterized by high rates of recurrence and mortality.
Glioblastoma (GBM), a grade IV brain tumor, is known for its heterogenicity and its …

The significant role of microRNAs in gliomas angiogenesis: a particular focus on molecular mechanisms and opportunities for clinical application

A Mafi, R Mannani, S Khalilollah, N Hedayati… - Cellular and Molecular …, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs with only 20–22 nucleic acids that inhibit gene
transcription and translation by binding to mRNA. MiRNAs have a diverse set of target genes …

Breaching barriers in glioblastoma. Part I: Molecular pathways and novel treatment approaches

A Miranda, M Blanco-Prieto, J Sousa, A Pais… - International journal of …, 2017 - Elsevier
Glioblastoma multiforme (GBM) is the most common primary brain tumour, and the most
aggressive in nature. The prognosis for patients with GBM remains poor, with a median …

DC‐AL GAN: Pseudoprogression and true tumor progression of glioblastoma multiform image classification based on DCGAN and AlexNet

M Li, H Tang, MD Chan, X Zhou, X Qian - Medical physics, 2020 - Wiley Online Library
Purpose Pseudoprogression (PsP) occurs in 20–30% of patients with glioblastoma
multiforme (GBM) after receiving the standard treatment. PsP exhibits similarities in shape …

Improve glioblastoma multiforme prognosis prediction by using feature selection and multiple kernel learning

Y Zhang, A Li, C Peng, M Wang - IEEE/ACM transactions on …, 2016 - ieeexplore.ieee.org
Glioblastoma multiforme (GBM) is a highly aggressive type of brain cancer with very low
median survival. In order to predict the patient's prognosis, researchers have proposed rules …

Anti-PD1 therapy induces lymphocyte-derived exosomal miRNA-4315 release inhibiting Bim-mediated apoptosis of tumor cells

N Guyon, D Garnier, J Briand, A Nadaradjane… - Cell Death & …, 2020 - nature.com
Anti-PD1 immunotherapy, as a single agent or in combination with standard
chemotherapies, has significantly improved the outcome of many patients with cancers …