[HTML][HTML] Update on occult hepatitis B virus infection

M Makvandi - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
The event of mutations in the surface antigen gene of hepatitis B virus (HBV) results in
undetectable hepatitis B surface antigen with positive/negative anti-hepatitis B core (anti …

Restoring, releasing or replacing adaptive immunity in chronic hepatitis B

MK Maini, AR Burton - Nature Reviews Gastroenterology & Hepatology, 2019 - nature.com
Multiple new therapeutic approaches are currently being developed to achieve sustained,
off-treatment suppression of HBV, a persistent hepatotropic infection that kills~ 2,000 people …

[HTML][HTML] Circulating and intrahepatic antiviral B cells are defective in hepatitis B

AR Burton, LJ Pallett, LE McCoy… - The Journal of …, 2018 - Am Soc Clin Investig
B cells are increasingly recognized as playing an important role in the ongoing control of
hepatitis B virus (HBV). The development of antibodies against the viral surface antigen …

[HTML][HTML] PD-1 blockade partially recovers dysfunctional virus–specific B cells in chronic hepatitis B infection

L Salimzadeh, N Le Bert, CA Dutertre… - The Journal of …, 2018 - Am Soc Clin Investig
Chronic HBV (CHB) infection suppresses virus-specific T cells, but its impact on humoral
immunity has been poorly analyzed. Here, we developed a dual-staining method that …

Molecular mechanisms underlying occult hepatitis B virus infection

J Samal, M Kandpal… - Clinical microbiology …, 2012 - Am Soc Microbiol
Chronic hepatitis B virus (HBV) infection is a complex clinical entity frequently associated
with cirrhosis and hepatocellular carcinoma (HCC). The persistence of HBV genomes in the …

Naked viruses that aren't always naked: quasi-enveloped agents of acute hepatitis

Z Feng, A Hirai-Yuki, KL McKnight… - Annual review of …, 2014 - annualreviews.org
Historically, viruses were considered to be either enveloped or nonenveloped. However,
recent work on hepatitis A virus and hepatitis E virus challenges this long-held tenet …

Hepatitis C virus particles and lipoprotein metabolism

P André, G Perlemuter, A Budkowska… - Seminars in liver …, 2005 - thieme-connect.com
The majority of infectious hepatitis C particles are present in the low-density fractions from
plasma of infected patients, suggesting an association of the virus with lipoproteins and the …

The multiple facets of FcRn in immunity

NM Stapleton, HK Einarsdóttir… - Immunological …, 2015 - Wiley Online Library
Summary The neonatal Fc receptor, FcRn, is best known for its role in transporting IgG in
various tissues, providing newborns with humoral immunity, and for prolonging the half‐life …

[PDF][PDF] Immune-mediated liver injury in hepatitis B virus infection

IS Oh, SH Park - Immune network, 2015 - synapse.koreamed.org
Five hepatitis viruses (hepatitis A to E) are the leading causes of liver disease worldwide.
Among them, hepatitis B virus (HBV) is responsible for approximately 350 million chronic …

[HTML][HTML] The option of HBIG-free prophylaxis against recurrent HBV

AN Fox, NA Terrault - Journal of hepatology, 2012 - Elsevier
Since the early 1990's, hepatitis B immune globulin (HBIG) has been central to the
prevention of hepatitis B virus (HBV) recurrence after liver transplantation. When used in …