4D flow MRI hemodynamic biomarkers for cerebrovascular diseases
Alterations in cerebral blood flow are common in several neurological diseases among the
elderly including stroke, cerebral small vessel disease, vascular dementia, and Alzheimer's …
elderly including stroke, cerebral small vessel disease, vascular dementia, and Alzheimer's …
4D flow MRI for non-invasive measurement of blood flow in the brain: a systematic review
AG Morgan, MJ Thrippleton… - Journal of Cerebral …, 2021 - journals.sagepub.com
The brain's vasculature is essential for brain health and its dysfunction contributes to the
onset and development of many dementias and neurological disorders. While numerous in …
onset and development of many dementias and neurological disorders. While numerous in …
Normative cerebral hemodynamics in middle-aged and older adults using 4D flow MRI: initial analysis of vascular aging
GS Roberts, A Peret, EM Jonaitis, RL Koscik… - Radiology, 2023 - pubs.rsna.org
Background Characterizing cerebrovascular hemodynamics in older adults is important for
identifying disease and understanding normal neurovascular aging. Four-dimensional (4D) …
identifying disease and understanding normal neurovascular aging. Four-dimensional (4D) …
In vivo pulsatility measurement of cerebral microcirculation in rodents using dynamic ultrasound localization microscopy
An increased pulse pressure, due to arteries stiffening with age and cardiovascular disease,
may lead to downstream brain damage in microvessels and cognitive decline. Brain-wide …
may lead to downstream brain damage in microvessels and cognitive decline. Brain-wide …
Cerebral arterial pulsatility is linked to hippocampal microvascular function and episodic memory in healthy older adults
Microvascular damage in the hippocampus is emerging as a central cause of cognitive
decline and dementia in aging. This could be a consequence of age-related decreases in …
decline and dementia in aging. This could be a consequence of age-related decreases in …
[HTML][HTML] Higher intracranial arterial pulsatility is associated with presumed imaging markers of the glymphatic system: An explorative study
L Xie, Y Zhang, H Hong, S Xu, L Cui, S Wang, J Li… - Neuroimage, 2024 - Elsevier
Background Arterial pulsation has been suggested as a key driver of paravascular
cerebrospinal fluid flow, which is the foundation of glymphatic clearance. However, whether …
cerebrospinal fluid flow, which is the foundation of glymphatic clearance. However, whether …
Maternal but not fetoplacental health can be improved by metformin in a murine diet‐induced model of maternal obesity and glucose intolerance
A Hufnagel, DS Fernandez‐Twinn… - The Journal of …, 2022 - Wiley Online Library
Maternal obesity is a global problem that increases the risk of short‐and long‐term adverse
outcomes for mother and child, many of which are linked to gestational diabetes mellitus …
outcomes for mother and child, many of which are linked to gestational diabetes mellitus …
Non‐invasive assessment of damping of blood flow velocity Pulsatility in cerebral arteries with MRI
T Arts, LP Onkenhout, RP Amier… - Journal of Magnetic …, 2022 - Wiley Online Library
Background Damping of heartbeat‐induced pressure pulsations occurs in large arteries
such as the aorta and extends to the small arteries and microcirculation. Since recently, 7 T …
such as the aorta and extends to the small arteries and microcirculation. Since recently, 7 T …
Diagnostic separation of conventional⩾ 50% carotid stenosis and near-occlusion with phase-contrast MRI
M Holmgren, A Henze, A Wåhlin… - European Stroke …, 2024 - journals.sagepub.com
Introduction: The aim of this study was to assess sensitivity, specificity and interrater
reliability of phase-contrast MRI (PC-MRI) for diagnosing carotid near-occlusion. Patients …
reliability of phase-contrast MRI (PC-MRI) for diagnosing carotid near-occlusion. Patients …
From 2D to 4D phase‐contrast MRI in the neurovascular system: will it be a quantum jump or a fancy decoration?
SW Youn, J Lee - Journal of Magnetic Resonance Imaging, 2022 - Wiley Online Library
Considering the crosstalk between the flow and vessel wall, hemodynamic assessment of
the neurovascular system may offer a well‐integrated solution for both diagnosis and …
the neurovascular system may offer a well‐integrated solution for both diagnosis and …