Natural quinone dyes: A review on structure, extraction techniques, analysis and application potential

B Dulo, K Phan, J Githaiga, K Raes… - Waste and Biomass …, 2021 - Springer
Synthetic dyes are by far the most widely applied colourants in industry. However,
environmental and sustainability considerations have led to an increasing efforts to …

Journey on naphthoquinone and anthraquinone derivatives: new insights in Alzheimer's disease

M Campora, V Francesconi, S Schenone, B Tasso… - Pharmaceuticals, 2021 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease that is characterized
by memory loss, cognitive impairment, and functional decline leading to dementia and …

Naphthoquinones and their derivatives: emerging trends in combating microbial pathogens

NS Mone, SA Bhagwat, D Sharma, M Chaskar… - Coatings, 2021 - mdpi.com
In the current era, an ever-emerging threat of multidrug-resistant (MDR) pathogens pose
serious health challenges to mankind. Researchers are uninterruptedly putting their efforts …

Ethnobotanical, Phytochemistry, and Pharmacological Activity of Onosma (Boraginaceae): An Updated Review

AA Jabbar, FO Abdullah, AO Hassan, Y Galali… - Molecules, 2022 - mdpi.com
The genus Onosma belongs to the Boraginaceae family and contains over 230 species. The
present review sheds light on the ethnopharmacology, phytoconstituents, bioactivity, and …

Onosma mutabilis: Phytochemical composition, antioxidant, cytotoxicity, and acute oral toxicity

AA Jabbar - Food Science & Nutrition, 2021 - Wiley Online Library
The traditional use of Onosma L. species as a remedy motivated scientists to discover great
biological/pharmacological potentials in this plant. In the current study, in addition to the …

1,4-Naphthoquinone (CNN1) Induces Apoptosis through DNA Damage and Promotes Upregulation of H2AFX in Leukemia Multidrug Resistant Cell Line

AJ de Sousa Portilho, EL da Silva… - International Journal of …, 2022 - mdpi.com
The multidrug resistance (MDR) phenotype is one of the major obstacles in the treatment of
chronic myeloid leukemia (CML) in advantage stages such as blast crisis. In this scenario …

Pharmacology, toxicity and pharmacokinetics of acetylshikonin: a review

Z Zhang, J Bai, Y Zeng, M Cai, Y Yao, H Wu… - Pharmaceutical …, 2020 - Taylor & Francis
Context Acetylshikonin, a naphthoquinone derivative, is mainly extracted from some species
of the family Boraginaceae, such as Lithospermum erythrorhizon Sieb. et Zucc., Arnebia …

Multiple biological activities of two Onosma species (O. sericea and O. stenoloba) and HPLC-MS/MS characterization of their phytochemical composition

JSK Stanković, R Ceylan, G Zengin, S Matić… - Industrial crops and …, 2020 - Elsevier
Members of the Onosma genus are widely used in folk medicine and they have great
interest in the pharmaceutical industry. In this study, phytochemical characterization …

Antibacterial naphthoquinone derivatives targeting resistant strain Gram-negative bacteria in biofilms

JS Novais, CS Moreira, ACJA Silva, RS Loureiro… - Microbial …, 2018 - Elsevier
The aims of this study were the planning, synthesis and in vitro evaluation of 2-hydroxy-3-
phenylsulfanylmethyl-[1, 4]-naphthoquinones against Gram-negative and Gram-positive …

Deoxyshikonin inhibited rotavirus replication by regulating autophagy and oxidative stress through SIRT1/FoxO1/Rab7 axis

H Huang, D Liao, B He, R Pu, Y Cui, G Zhou - Microbial Pathogenesis, 2023 - Elsevier
Background Rotavirus (RV) is a double-stranded RNA virus. RV prevention and treatment
remain a major public health problem due to the lack of clinically specific drugs …