Multifaceted strategies for alleviating Pseudomonas aeruginosa infection by targeting protease activity: Natural and synthetic molecules

F Khan - International Journal of Biological Macromolecules, 2024 - Elsevier
Pseudomonas aeruginosa has become a top-priority pathogen in the health sector because
it is ubiquitous, has high metabolic/genetic versatility, and is identified as an opportunistic …

[HTML][HTML] Coumarins: Quorum Sensing and Biofilm Formation Inhibition

ER El-Sawy, MS Abdel-Aziz, H Abdelmegeed, G Kirsch - Molecules, 2024 - mdpi.com
Quorum sensing (QS) is a bacterial cell-to-cell communication mechanism that plays an
essential role in bacterial pathogenesis. QS governs bacterial behavior and controls biofilm …

Multi-targeting of virulence factors of P. aeruginosa by β-lactam antibiotics to combat antimicrobial resistance

FA Qais, N Parveen, I Ahmad, FM Husain… - Journal of …, 2024 - Taylor & Francis
Antimicrobial resistance poses a significant challenge to public health, especially in
developing countries, due to a substantial rise in bacterial resistance. This situation has …

Hydroxychloroquine interaction with phosphoinositide 3-kinase modulates prostate cancer growth in bone microenvironment: In vitro and molecular dynamics based …

KM Abdullah, G Sharma, FA Qais, I Khan… - International Journal of …, 2024 - Elsevier
Patients with advanced prostate cancer (PCa) are more likely to develop bone metastases.
Tumor cells thrive in the bone microenvironment, interacting with osteoblasts and …

Mangiferin alleviates Quorum sensing regulated biofilm formation and virulence factor production in pathogenic bacteria: in vitro and in silico investigation

NA Al-Shabib, FM Husain, NM Ashraf, M Arshad… - Process …, 2024 - Elsevier
Quorum sensing (QS) is a crucial mechanism employed by bacteria for intercellular
communication, regulating various physiological processes including biofilm formation …

Management of virulence in Pseudomonas aeruginosa and Serratia marcescens using environmentally-friendly titanium dioxide nanoparticles

FA Qais, M Altaf, I Ahmad - RSC advances, 2023 - pubs.rsc.org
Antimicrobial resistance (AMR), a condition in which the efficacy of antimicrobial drugs in
fighting microorganisms is reduced, has become a global challenge. Multidrug resistance …

Control of Biofilm and Virulence in Pseudomonas aeruginosa by Green-Synthesized Titanium–Cerium Nanocomposites

M Altaf, N Parveen, FA Qais, KM Abdullah… - Microbiology …, 2023 - mdpi.com
Antimicrobial resistance (AMR) has become a critical global health challenge. Infections,
particularly those caused by multidrug-resistant (MDR) pathogens, rank among the top …

Antimycobacterial Drugs as a Novel Strategy to Inhibit Pseudomonas aeruginosa Virulence Factors and Combat Antibiotic Resistance: A Molecular Simulation Study

R Anwer - Microbiology Research, 2024 - mdpi.com
Antimicrobial resistance poses a severe threat, particularly in developing countries where
the ready availability of drugs and increased consumption lead to improper antibiotic usage …

Antibacterial and anti-biofilm efficacy of 1, 4-naphthoquinone against Chromobacterium violaceum: an in vitro and in silico investigation

I Ahmad - Archives of Microbiology, 2025 - Springer
Antimicrobial resistance (AMR) is an urgent worldwide health concern, requiring the
exploration for novel antimicrobial interventions. A Gram-negative bacterium …

[引用][C] Multi-targeted Virtual Screening of Phytocompounds of Rauwolfia serpentina Against Caspase-8, BACE, and AChE for the Treatment of Neurodegenerative …

NH Aljarba, FA Qais… - Journal of …, 2023 - King Salman Center for Disability …