Structures and general transport mechanisms by the major facilitator superfamily (MFS)
The major facilitator superfamily (MFS) is the largest known superfamily of secondary active
transporters. MFS transporters are responsible for transporting a broad spectrum of …
transporters. MFS transporters are responsible for transporting a broad spectrum of …
Paramagnetic chemical probes for studying biological macromolecules
Paramagnetic chemical probes have been used in electron paramagnetic resonance (EPR)
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …
and nuclear magnetic resonance (NMR) spectroscopy for more than four decades. Recent …
Lipid membrane mimetics in functional and structural studies of integral membrane proteins
Integral membrane proteins (IMPs) fulfill important physiological functions by providing cell–
environment, cell–cell and virus–host communication; nutrients intake; export of toxic …
environment, cell–cell and virus–host communication; nutrients intake; export of toxic …
Nanomolar Pulse Dipolar EPR Spectroscopy in Proteins: CuII–CuII and Nitroxide–Nitroxide Cases
K Ackermann, JL Wort, BE Bode - The Journal of Physical …, 2021 - ACS Publications
The study of ever more complex biomolecular assemblies implicated in human health and
disease is facilitated by a suite of complementary biophysical methods. Pulse dipolar …
disease is facilitated by a suite of complementary biophysical methods. Pulse dipolar …
Structure and mechanism of membrane transporters
L Guan - Scientific Reports, 2022 - nature.com
Membrane transporters are an important group of proteins in physiology and disease. Their
functions make them common drug targets, but their location in the lipid bilayers poses a …
functions make them common drug targets, but their location in the lipid bilayers poses a …
A general model to optimise Cu II labelling efficiency of double-histidine motifs for pulse dipolar EPR applications
JL Wort, K Ackermann, DG Norman… - Physical Chemistry …, 2021 - pubs.rsc.org
Electron paramagnetic resonance (EPR) distance measurements are making increasingly
important contributions to studies of biomolecules underpinning health and disease by …
important contributions to studies of biomolecules underpinning health and disease by …
Molecular Dynamics Simulations Based on Newly Developed Force Field Parameters for Cu2+ Spin Labels Provide Insights into Double-Histidine-Based Double …
Electron paramagnetic resonance (EPR) in combination with the recently developed double-
histidine (dHis)-based Cu2+ spin labeling has provided valuable insights into protein …
histidine (dHis)-based Cu2+ spin labeling has provided valuable insights into protein …
Characteristics of Gd (III) spin labels for the study of protein conformations
Gd (III) complexes are currently established as spin labels for structural studies of
biomolecules using pulse dipolar electron paramagnetic resonance (PD-EPR) techniques …
biomolecules using pulse dipolar electron paramagnetic resonance (PD-EPR) techniques …
Triggered Functional Dynamics of AsLOV2 by Time‐Resolved Electron Paramagnetic Resonance at High Magnetic Fields
We present time‐resolved Gd− Gd electron paramagnetic resonance (TiGGER) at 240 GHz
for tracking inter‐residue distances during a protein's mechanical cycle in the solution state …
for tracking inter‐residue distances during a protein's mechanical cycle in the solution state …
A Comparative Study of Nitroxide‐Based Biradicals for Dynamic Nuclear Polarization in Cellular Environments
BE Ackermann, BJ Lim, N Elathram… - …, 2022 - Wiley Online Library
Dynamic nuclear polarization (DNP) is a powerful tool to enhance the NMR signals of
molecules by transferring polarization from unpaired electron spins to nuclei through …
molecules by transferring polarization from unpaired electron spins to nuclei through …