Lipoprotein lipase (LPL) catalyses the hydrolysis of the triacylglycerol component of
circulating chylomicrons and very low density lipoproteins, thereby providing non-esterified …

Lipoprotein lipase (LPL) regulates the plasma levels of triglyceride and HDL. Three aspects
are reviewed. 1) Clinical implications of human LPL gene variations: common mutations and …

Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors
that regulate lipid and lipoprotein metabolism, glucose homeostasis and inflammation. The …

Recent data suggest that plasma leptin may represent a cardiovascular risk factor in diabetic
patients. To gain further insight into the role of leptin in atherogenesis associated with …

1. Introduction acids and 2-monoacylglycerols for tissue utilization [3, 4]. Due to the large
size of its substrates, the physiological site Atherosclerosis, the underlying cause of heart …

We previously described the expression of CD36 and LPL by breast cancer (BC) cells and
tissues and the growth-promoting effect of VLDL observed only in the presence of LPL. We …

There is increasing evidence that microRNAs (miRNAs) play important roles in cell
proliferation, apoptosis and differentiation that accompany inflammatory responses …

The pathogenesis of atherosclerosis involves multiple cellular events, including endothelial
cell dysfunction, inflammation, proliferation of vascular smooth muscle cells and matrix …

Objective The novel description of antibodies to lipoprotein lipase (anti‐LPL) associated with
dyslipoproteinemia prompted us to analyze the association of anti‐LPL with clinical and …

Highlights•Lipoprotein lipase plays a key part in human triglyceride metabolism.•Certain
liver-derived proteins stimulate or inhibit LPL activity.•Novel small-molecule and gene …