Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …
Emerging droplet microfluidics
Droplet microfluidics generates and manipulates discrete droplets through immiscible
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …
Ultrahigh-Throughput Enzyme Engineering and Discovery in In Vitro Compartments
Novel and improved biocatalysts are increasingly sourced from libraries via experimental
screening. The success of such campaigns is crucially dependent on the number of …
screening. The success of such campaigns is crucially dependent on the number of …
Microfluidics for drug development: from synthesis to evaluation
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …
delivery, and drug evaluation. Compared with conventional drug development procedures …
Recent advances in droplet microfluidics
Y Ding, PD Howes, AJ deMello - Analytical chemistry, 2019 - ACS Publications
Prominent within this technology set are droplet-based microfluidic systems, 3 in which
passive microfluidic structures are used to rapidly generate and manipulate subnanoliter …
passive microfluidic structures are used to rapidly generate and manipulate subnanoliter …
Microfluidic devices for drug delivery systems and drug screening
S Damiati, UB Kompella, SA Damiati, R Kodzius - Genes, 2018 - mdpi.com
Microfluidic devices present unique advantages for the development of efficient drug carrier
particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening …
particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening …
Single-cell analysis and sorting using droplet-based microfluidics
We present a droplet-based microfluidics protocol for high-throughput analysis and sorting
of single cells. Compartmentalization of single cells in droplets enables the analysis of …
of single cells. Compartmentalization of single cells in droplets enables the analysis of …
Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics
N Shembekar, C Chaipan, R Utharala, CA Merten - Lab on a Chip, 2016 - pubs.rsc.org
Droplet-based microfluidics enables assays to be carried out at very high throughput (up to
thousands of samples per second) and enables researchers to work with very limited …
thousands of samples per second) and enables researchers to work with very limited …
Effect-directed analysis supporting monitoring of aquatic environments—an in-depth overview
Aquatic environments are often contaminated with complex mixtures of chemicals that may
pose a risk to ecosystems and human health. This contamination cannot be addressed with …
pose a risk to ecosystems and human health. This contamination cannot be addressed with …
Development and future of droplet microfluidics
Over the past two decades, advances in droplet-based microfluidics have facilitated new
approaches to process and analyze samples with unprecedented levels of precision and …
approaches to process and analyze samples with unprecedented levels of precision and …