Biomarkers of acute kidney injury
JC Sirota, J Klawitter, CL Edelstein - Journal of toxicology, 2011 - Wiley Online Library
Acute kidney injury (AKI) is a common problem in both the inpatient and outpatient setting
and often results from drug toxicities. Traditional methods of identifying AKI, through …
and often results from drug toxicities. Traditional methods of identifying AKI, through …
Renal cell carcinoma: a study through NMR-based metabolomics combined with transcriptomics
R Ragone, F Sallustio, S Piccinonna, M Rutigliano… - Diseases, 2016 - mdpi.com
Renal cell carcinoma (RCC) is a heterogeneous cancer often showing late symptoms. Until
now, some candidate protein markers have been proposed for its diagnosis. Metabolomics …
now, some candidate protein markers have been proposed for its diagnosis. Metabolomics …
Calcineurin inhibitor minimization protocols in liver transplantation
SA Farkas, AA Schnitzbauer, G Kirchner… - Transplant …, 2009 - Wiley Online Library
Liver transplant recipients are at increasingly high risk for suffering from impaired renal
function and probable need of renal replacement therapy. Extended criteria organs and …
function and probable need of renal replacement therapy. Extended criteria organs and …
Immunotherapy in elderly transplant recipients: a guide to clinically significant drug interactions
DRJ Kuypers - Drugs & aging, 2009 - Springer
Abstract Currently,> 50% of candidates for solid organ transplantation in Europe and the US
are aged> 50 years while approximately 15% of potential recipients are aged≥ 65 years …
are aged> 50 years while approximately 15% of potential recipients are aged≥ 65 years …
Tacrolimus modulates TGF-β signaling to induce epithelial-mesenchymal transition in human renal proximal tubule epithelial cells
J Bennett, H Cassidy, C Slattery, MP Ryan… - Journal of Clinical …, 2016 - mdpi.com
Epithelial-mesenchymal transition (EMT), a process which describes the trans-differentiation
of epithelial cells into motile mesenchymal cells, is pivotal in stem cell behavior …
of epithelial cells into motile mesenchymal cells, is pivotal in stem cell behavior …
Identification of urinary metabolites that distinguish membranous lupus nephritis from proliferative lupus nephritis and focal segmental glomerulosclerosis
LE Romick-Rosendale, HI Brunner, MR Bennett… - Arthritis research & …, 2011 - Springer
Introduction Systemic lupus erythematosus (SLE or lupus) is a chronic autoimmune disease,
and kidney involvement with SLE, aka lupus nephritis (LN), is a frequent and severe …
and kidney involvement with SLE, aka lupus nephritis (LN), is a frequent and severe …
A high-throughput U-HPLC–MS/MS assay for the quantification of mycophenolic acid and its major metabolites mycophenolic acid glucuronide and mycophenolic acid …
J Klepacki, J Klawitter, J Bendrick-Peart… - … of Chromatography B, 2012 - Elsevier
Mycophenolic acid (MPA) is used as an immunosuppressant after organ transplantation and
for the treatment of immune diseases. There is increasing evidence that therapeutic drug …
for the treatment of immune diseases. There is increasing evidence that therapeutic drug …
Toxicodynamic effects of ciclosporin are reflected by metabolite profiles in the urine of healthy individuals after a single dose
J Klawitter, M Haschke, C Kahle… - British journal of …, 2010 - Wiley Online Library
WHAT IS ALREADY KNOWN ABOUT THE SUBJECT• Ciclosporin's nephrotoxicity initially
targets the proximal tubule and is, at least in part, driven by increased formation of oxygen …
targets the proximal tubule and is, at least in part, driven by increased formation of oxygen …
Urinary metabolomics in newborns and infants
V Fanos, R Antonucci, L Barberini… - Advances in clinical …, 2012 - books.google.com
Metabolomics is a new approach based on the systematic study of the full complement of
metabolites in a biological sample. This technology consists of two sequential steps:(1) an …
metabolites in a biological sample. This technology consists of two sequential steps:(1) an …