Inherited retinal diseases (IRDs) are a heterogenous group of orphan eye diseases that
typically result from monogenic mutations and are considered attractive targets for gene …

Aging and associated neurodegenerative diseases are accompanied by the decline of
several brain functions including cognitive abilities. Progressive deleterious changes at …

Nonalcoholic fatty liver disease (NAFLD) is prevalent worldwide, while no pharmaceutical
treatment has been approved. Natural herbs are promising for their amelioration effect on …

Inherited retinal diseases (IRDs) are associated with mutations in over 250 genes and
represent a major cause of irreversible blindness worldwide. While gene augmentation or …

Neurodegenerative diseases are closely related to brain function and the progression of the
diseases are irreversible. Due to brain tissue being not easy to acquire, the study of the …

Pyroptosis is a form of cell death mediated by inflammasomes and gasdermins, and the
relevance of pyroptosis to neurodegenerative diseases is currently receiving increasing …

A herpesvirus virion is composed of a viral genomic DNA-containing capsid surrounded by a
viral envelope with glycoprotein spikes on its surface. Located between the capsid and the …

Background: Oxidative stress is related to oncogenic transformation in kidney renal clear cell
carcinoma (KIRC). We intended to identify a prognostic antioxidant gene signature and …

Among posttranslational modifications, directed proteolytic processes have the strongest
impact on protein integrity. They are executed by a variety of cellular machineries and lead …

Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer with
a poor prognosis. 5-methylcytosine (m5C) modification plays a nonnegligible role in tumor …