Tumorigenesis mechanisms found in hereditary renal cell carcinoma: a review

BR Webster, N Gopal, MW Ball - Genes, 2022 - mdpi.com
Renal cell carcinoma is a heterogenous cancer composed of an increasing number of
unique subtypes each with their own cellular and tumor behavior. The study of hereditary …

French AFU Cancer Committee Guidelines-update 2022-2024: management of kidney cancer

P Bigot, P Barthelemy, R Boissier, ZE Khene… - Progrès en Urologie, 2022 - Elsevier
Aim To update the recommendations for the management of kidney cancers. Methods A
systematic review of the literature was conducted from 2015 to 2022. The most relevant …

Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer

DR Crooks, N Maio, M Lang, CJ Ricketts, CD Vocke… - Science …, 2021 - science.org
Understanding the mechanisms of the Warburg shift to aerobic glycolysis is critical to
defining the metabolic basis of cancer. Hereditary leiomyomatosis and renal cell carcinoma …

Small renal mass surveillance: histology-specific growth rates in a biopsy-characterized cohort

A Finelli, DC Cheung, A Al-Matar, AJ Evans… - European urology, 2020 - Elsevier
Background Most reports of active surveillance (AS) of small renal masses (SRMs) lack
biopsy confirmation, and therefore include benign tumors and different subtypes of renal cell …

Clinical practice guidelines for the diagnosis and surveillance of BAP1 tumour predisposition syndrome

F Lalloo, A Kulkarni, C Chau, M Nielsen… - European Journal of …, 2023 - nature.com
Abstract BRCA1-associated protein-1 (BAP1) is a recognised tumour suppressor gene.
Germline BAP1 pathogenic/likely pathogenic variants are associated with predisposition to …

[HTML][HTML] Treatment strategies for hereditary kidney cancer: current recommendations and updates

S Singh, A Chaurasia, N Gopal… - Discovery …, 2022 - discoverymedicine.com
A subset of renal tumors (5-8%) are associated with syndromes such as von Hippel-Lindau
(VHL) syndrome, Birt-Hogg-Dubé syndrome (BHD), tuberous sclerosis complex (TSC) …

An MRI-based radiomics model to predict clear cell renal cell carcinoma growth rate classes in patients with von Hippel-Lindau syndrome

PY Anari, N Lay, N Gopal, A Chaurasia, S Samimi… - Abdominal …, 2022 - Springer
Purpose Upfront knowledge of tumor growth rates of clear cell renal cell carcinoma in von
Hippel-Lindau syndrome (VHL) patients can allow for a more personalized approach to …

Genetic alterations in renal cancers: Identification of the mechanisms underlying cancer initiation and progression and of therapeutic targets

U Testa, E Pelosi, G Castelli - Medicines, 2020 - mdpi.com
Renal cell cancer (RCC) involves three most recurrent sporadic types: clear-cell RCC (70–
75%, CCRCC), papillary RCCC (10–15%, PRCC), and chromophobe RCC (5%, CHRCC) …

A 25 year perspective on the evolution and advances in an understanding of the biology, evaluation and treatment of kidney cancer

DM Geynisman, JK Maranchie, MW Ball… - … Oncology: Seminars and …, 2021 - Elsevier
The diagnosis, evaluation and management of patients with renal cell carcinoma has
transformed in the 21st century. Utilizing biological discoveries and technological advances …

Radiomics to better characterize small renal masses

T Kuusk, JB Neves, M Tran, A Bex - World Journal of Urology, 2021 - Springer
Purpose Radiomics is a specific field of medical research that uses programmable
recognition tools to extract objective information from standard images to combine with …