Adolescents' media use represents a normative need for information, communication,
recreation and functionality, yet problematic Internet use has increased. Given the arguably …

OBJECTIVES: Acute severe steroid-refractory ulcerative colitis (UC) carries a poor prognosis
and requires optimal management. A systematic review and meta-analysis were conducted …

Introduction Efficacy of mepolizumab, an anti-interleukin-5 monoclonal antibody, was
demonstrated in randomised controlled trials; data on its real-world impact in routine clinical …

Background Fremanezumab has demonstrated to be effective, safe, and tolerated in the
prevention of episodic or chronic migraine (CM) in randomized, placebo-controlled trials …

Open Dialogue (OD) is a family-oriented early intervention approach which has
demonstrated good outcomes in the treatment of first-episode psychosis (FEP) …

Randomized controlled trials (RCTs) are the gold‐standard for benefit–risk assessments
during drug approval processes. Real‐word data (RWD) and the resulting real‐world …

Atopic dermatitis (AD) is a chronic, inflammatory skin disorder that most frequently occurs in
children, but it can also affect adults. Even though most AD cases can be managed with …

Purpose Efforts to promote the health and well-being of military veterans have been
criticised for being inadequately informed of veterans' most pressing needs as they separate …

Real-world studies include a broader patient population for a longer duration than
randomised controlled trials (RCTs) and can provide relevant insights for clinical practice …

Introduction The purpose of this study was to assess the effectiveness of advanced-(a-HCL)
vs. standard-hybrid closed-loop (s-HCL) systems use up to 6 months of treatment in a real …