Inflammatory bowel disease (IBD) affects 6.8 million people globally. A variety of factors
have been implicated in IBD pathogenesis, including host genetics, immune dysregulation …

Inflammatory bowel disease (IBD)-related colorectal cancer (CRC) is responsible for
approximately 2% of the annual mortality from CRC overall, but 10–15% of the annual …

This study investigated the effects of water-soluble polysaccharide extracted from the
sporoderm-removed spores of Ganoderma lucidum (GLP) against AOM/DSS-induced …

The gastrointestinal tract is coated by a thick layer of mucus that forms the front line of innate
host defense. Mucus consists of high molecular weight glycoproteins called mucins that are …

The connection between inflammation and tumorigenesis is well-established and in the last
decade has received a great deal of supporting evidence from genetic, pharmacological …

Background Colorectal cancer (CRC) is one of the leading cause of cancer deaths
worldwide. Since CRC is largely asymptomatic until alarm features develop to advanced …

The gastrointestinal microbiome plays a pivotal role in physiological homeostasis of the
intestine as well as in the pathophysiology of diseases including inflammatory bowel …

Chronic inflammation is linked to the development of multiple cancers, including those of the
colon. Inflammation in the gut induces carcinogenic mutagenesis and promotes colorectal …

Connection between inflammation and cancer is a rapidly developing field. Epidemiological
data suggests that inflammation along with distinct arms of host immune system plays a very …

Instability in the composition of gut bacterial communities (dysbiosis) has been linked to
common human intestinal disorders, such as Crohn's disease and colorectal cancer. Here …