[HTML][HTML] Endoplasmic reticulum stress in metabolic disorders
R Ghemrawi, SF Battaglia-Hsu, C Arnold - Cells, 2018 - mdpi.com
Metabolic disorders have become among the most serious threats to human health, leading
to severe chronic diseases such as obesity, type 2 diabetes, and non-alcoholic fatty liver …
to severe chronic diseases such as obesity, type 2 diabetes, and non-alcoholic fatty liver …
Role of endoplasmic reticulum stress in hepatic glucose and lipid metabolism and therapeutic strategies for metabolic liver disease
W Zheng, Q Sun, L Li, Y Cheng, Y Chen, M Lv… - International …, 2022 - Elsevier
The endoplasmic reticulum is the most abundant membrane organelle in eukaryotic cells. It
is an important site of membrane and secretory protein folding and glycolipid synthesis and …
is an important site of membrane and secretory protein folding and glycolipid synthesis and …
[HTML][HTML] Salubrinal promotes phospho-eIF2α-dependent activation of UPR leading to autophagy-mediated attenuation of iron-induced insulin resistance
Identification of new mechanisms mediating insulin sensitivity is important to allow validation
of corresponding therapeutic targets. In this study, we first used a cellular model of skeletal …
of corresponding therapeutic targets. In this study, we first used a cellular model of skeletal …
[PDF][PDF] Examination of Endoplasmic Reticulum Stress, the Unfolded Protein Response and Autophagy in Iron Overload-Induced Insulin Resistance
KNY Nguyen - 2023 - yorkspace.library.yorku.ca
Identification of new mechanisms mediating insulin sensitivity is important to allow validation
of corresponding therapeutic targets. In this study, I first used a cellular model of skeletal …
of corresponding therapeutic targets. In this study, I first used a cellular model of skeletal …
Differential unfolded protein response in skeletal muscle from non-diabetic glucose tolerant or intolerant patients with obesity before and after bariatric surgery
C Marciniak, C Duhem, A Boulinguiez, V Raverdy… - Acta Diabetologica, 2020 - Springer
Aims Not all people with obesity become glucose intolerant, suggesting differential
activation of cellular pathways. The unfolded protein response (UPR) may contribute to the …
activation of cellular pathways. The unfolded protein response (UPR) may contribute to the …
Significance of Triazole in Medicinal Chemistry: Advancement in Drug Design, Reward and Biological Activity
M Ajmal, AK Mahato, M Khan, S Rawat… - Chemistry & …, 2024 - Wiley Online Library
One of the triazole tautomers, 1, 2, 4‐triazole derivatives, has a wide range of biological
activities that suggest its potential therapeutic utility in medicinal chemistry. These actions …
activities that suggest its potential therapeutic utility in medicinal chemistry. These actions …
Rôle des anses intestinales dans les effets métaboliques du gastric bypass: apport du modèle porcin
C Marciniak - 2021 - theses.hal.science
La chirurgie bariatrique s' est largement répandue depuis plus de 20 ans et a transformé la
prise en charge de l'obésité et de ses comorbidités métaboliques (diabète de type 2 …
prise en charge de l'obésité et de ses comorbidités métaboliques (diabète de type 2 …