Comparative analysis and prediction of quorum-sensing peptides using feature representation learning and machine learning algorithms
Quorum-sensing peptides (QSPs) are the signal molecules that are closely associated with
diverse cellular processes, such as cell–cell communication, and gene expression …
diverse cellular processes, such as cell–cell communication, and gene expression …
Meta-4mCpred: a sequence-based meta-predictor for accurate DNA 4mC site prediction using effective feature representation
DNA N4-methylcytosine (4mC) is an important genetic modification and plays crucial roles in
differentiation between self and non-self DNA and in controlling DNA replication, cell cycle …
differentiation between self and non-self DNA and in controlling DNA replication, cell cycle …
mAHTPred: a sequence-based meta-predictor for improving the prediction of anti-hypertensive peptides using effective feature representation
Motivation Cardiovascular disease is the primary cause of death globally accounting for
approximately 17.7 million deaths per year. One of the stakes linked with cardiovascular …
approximately 17.7 million deaths per year. One of the stakes linked with cardiovascular …
Exploring sequence-based features for the improved prediction of DNA N4-methylcytosine sites in multiple species
Motivation As one of important epigenetic modifications, DNA N4-methylcytosine (4mC) is
recently shown to play crucial roles in restriction–modification systems. For better …
recently shown to play crucial roles in restriction–modification systems. For better …
An algorithmic perspective of de novo cis-regulatory motif finding based on ChIP-seq data
Transcription factors are proteins that bind to specific DNA sequences and play important
roles in controlling the expression levels of their target genes. Hence, prediction of …
roles in controlling the expression levels of their target genes. Hence, prediction of …
DOOR 2.0: presenting operons and their functions through dynamic and integrated views
We have recently developed a new version of the DOOR operon database, DOOR 2.0,
which is available online at http://csbl. bmb. uga. edu/DOOR/and will be updated on a …
which is available online at http://csbl. bmb. uga. edu/DOOR/and will be updated on a …
DMINDA 2.0: integrated and systematic views of regulatory DNA motif identification and analyses
Motivation Motif identification and analyses are important and have been long-standing
computational problems in bioinformatics. Substantial efforts have been made in this field …
computational problems in bioinformatics. Substantial efforts have been made in this field …
Snowprint: a predictive tool for genetic biosensor discovery
S d'Oelsnitz, SK Stofel, JD Love… - Communications …, 2024 - nature.com
Bioengineers increasingly rely on ligand-inducible transcription regulators for chemical-
responsive control of gene expression, yet the number of regulators available is limited …
responsive control of gene expression, yet the number of regulators available is limited …
Autosomal Recessive Cerebellar Atrophy and Spastic Ataxia in Patients With Pathogenic Biallelic Variants in GEMIN5
The hereditary ataxias are a heterogenous group of disorders with an increasing number of
causative genes being described. Due to the clinical and genetic heterogeneity seen in …
causative genes being described. Due to the clinical and genetic heterogeneity seen in …
DOOR: a prokaryotic operon database for genome analyses and functional inference
The rapid accumulation of fully sequenced prokaryotic genomes provides unprecedented
information for biological studies of bacterial and archaeal organisms in a systematic …
information for biological studies of bacterial and archaeal organisms in a systematic …