Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy in mice
AR Smith, F Rizvi, E Everton, A Adeagbo, S Wu… - Nature …, 2024 - nature.com
Primary human hepatocyte (PHH) transplantation is a promising alternative to liver
transplantation, whereby liver function could be restored by partial repopulation of the …
transplantation, whereby liver function could be restored by partial repopulation of the …
VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis
The liver is known for its remarkable regenerative ability through proliferation of hepatocytes.
Yet, during chronic injury or severe hepatocyte death, proliferation of hepatocytes is …
Yet, during chronic injury or severe hepatocyte death, proliferation of hepatocytes is …