A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …

Maintenance of gastrointestinal health is challenging as it requires balancing multifaceted
processes within the highly complex and dynamic ecosystem of the gastrointestinal tract …

Background: Head and neck squamous cell carcinoma (HNSCC) is the seventh most
common type of cancer worldwide. Its highly aggressive and heterogeneous nature and …

Cell-free DNA (cfDNA) in human plasma provides access to molecular information about the
pathological processes in the organs or tumors from which it originates. These DNA …

Background Research has indicated that the emergence of Schwann cells around
premalignant lesions of colon cancer might be an early indicator promoting the onset of …

Purpose Colonoscopy and the fecal immunochemical test (FIT) are currently the most widely
used screening modalities for colorectal cancer (CRC), however, both with their own …

Simple Summary The influence of nerves on different types of cancers, including colorectal
cancer, is increasingly recognized. The intestines are highly innervated, both from outside …

Background Colon cancer stem cells (CSCs), considered responsible for tumor initiation and
cancer relapse, are constantly exposed to regulatory cues emanating from neighboring cells …

The gastrointestinal tract comprises a complex ecosystem with extensive opportunities for
functional interactions between neoplastic epithelial cells and stromal, immune, neuronal …

Colorectal cancer (CRC) invasion within the large intestine wall results in the replacement of
normal tissue architecture by tumour mass. Cancer cells digest the extracellular matrix …