Commensal fungi in health and disease

JJ Limon, JH Skalski, DM Underhill - Cell host & microbe, 2017 - cell.com
Fungi are increasingly being recognized as common members of the microbiomes found on
nearly all mucosal surfaces, and interest is growing in understanding how these organisms …

Forgotten fungi—the gut mycobiome in human health and disease

CE Huseyin, PW O'Toole, PD Cotter… - FEMS Microbiology …, 2017 - academic.oup.com
The human body is home to a complex and diverse microbial ecosystem that plays a central
role in host health. This includes a diversity of fungal species that is collectively referred to …

RESCRIPt: Reproducible sequence taxonomy reference database management

MS Robeson, DR O'Rourke, BD Kaehler… - PLoS computational …, 2021 - journals.plos.org
Nucleotide sequence and taxonomy reference databases are critical resources for
widespread applications including marker-gene and metagenome sequencing for …

Standardized multi-omics of Earth's microbiomes reveals microbial and metabolite diversity

JP Shaffer, LF Nothias, LR Thompson, JG Sanders… - Nature …, 2022 - nature.com
Despite advances in sequencing, lack of standardization makes comparisons across studies
challenging and hampers insights into the structure and function of microbial communities …

Maturation of the gut microbiome during the first year of life contributes to the protective farm effect on childhood asthma

M Depner, DH Taft, PV Kirjavainen, KM Kalanetra… - Nature medicine, 2020 - nature.com
Growing up on a farm is associated with an asthma-protective effect, but the mechanisms
underlying this effect are largely unknown. In the Protection against Allergy: Study in Rural …

Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin

NA Bokulich, BD Kaehler, JR Rideout, M Dillon… - Microbiome, 2018 - Springer
Background Taxonomic classification of marker-gene sequences is an important step in
microbiome analysis. Results We present q2-feature-classifier (https://github. com/qiime2/q2 …

Biodiversity of key-stone phylotypes determines crop production in a 4-decade fertilization experiment

K Fan, M Delgado-Baquerizo, X Guo, D Wang… - The ISME …, 2021 - academic.oup.com
Cropping systems have fertilized soils for decades with undetermined consequences for the
productivity and functioning of terrestrial ecosystems. One of the critical unknowns is the role …

How quantitative is metabarcoding: A meta‐analytical approach

PD Lamb, E Hunter, JK Pinnegar, S Creer… - Molecular …, 2019 - Wiley Online Library
Metabarcoding has been used in a range of ecological applications such as taxonomic
assignment, dietary analysis and the analysis of environmental DNA. However, after a …

Intestinal fungi contribute to development of alcoholic liver disease

AM Yang, T Inamine, K Hochrath… - The Journal of …, 2017 - Am Soc Clin Investig
Chronic liver disease with cirrhosis is the 12th leading cause of death in the United States,
and alcoholic liver disease accounts for approximately half of all cirrhosis deaths. Chronic …

Accurate estimation of fungal diversity and abundance through improved lineage-specific primers optimized for Illumina amplicon sequencing

DL Taylor, WA Walters, NJ Lennon… - Applied and …, 2016 - Am Soc Microbiol
While high-throughput sequencing methods are revolutionizing fungal ecology, recovering
accurate estimates of species richness and abundance has proven elusive. We sought to …