Multifunctional roles and pharmacological potential of β-sitosterol: Emerging evidence toward clinical applications

Z Khan, N Nath, A Rauf, TB Emran, S Mitra… - Chemico-Biological …, 2022 - Elsevier
Currently, available therapeutic medications are both costly as well as not entirely promising
in terms of potency. So, new candidates from natural resources are of research interest to …

Phytochemicals, nutrition, metabolism, bioavailability, and health benefits in lettuce—A comprehensive review

M Shi, J Gu, H Wu, A Rauf, TB Emran, Z Khan, S Mitra… - Antioxidants, 2022 - mdpi.com
Lettuce is one of the most famous leafy vegetables worldwide with lots of applications from
food to other specific uses. There are different types in the lettuce group for consumers to …

[HTML][HTML] Exploring the journey of emodin as a potential neuroprotective agent: novel therapeutic insights with molecular mechanism of action

S Mitra, J Anjum, M Muni, R Das, A Rauf, F Islam… - Biomedicine & …, 2022 - Elsevier
Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants,
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …

[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders

MT Kabir, MH Rahman, M Shah, MR Jamiruddin… - Biomedicine & …, 2022 - Elsevier
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …

[HTML][HTML] l-carnitine: Nutrition, pathology, and health benefits

AH Alhasaniah - Saudi Journal of Biological Sciences, 2023 - Elsevier
Carnitine is a medically needful nutrient that contributes in the production of energy and the
metabolism of fatty acids. Bioavailability is higher in vegetarians than in people who eat …

Investigating polyphenol nanoformulations for therapeutic targets against diabetes mellitus

F Islam, JF Khadija, MR Islam, S Shohag… - Evidence‐Based …, 2022 - Wiley Online Library
Diabetes mellitus (DM) is a fatal metabolic disorder, and its prevalence has escalated in
recent decades to a greater extent. Since the incidence and severity of the disease are …

Challenges and opportunities of metal chelation therapy in trace metals overload-induced Alzheimer's disease

V Chaudhari, S Bagwe-Parab, HS Buttar, S Gupta… - Neurotoxicity …, 2023 - Springer
Essential trace metals like zinc (Zn), iron (Fe), and copper (Cu) play an important
physiological role in the metabolomics and healthy functioning of body organs, including the …

Tacrine derivatives in neurological disorders: Focus on molecular mechanisms and neurotherapeutic potential

S Mitra, M Muni, NJ Shawon, R Das… - Oxidative Medicine …, 2022 - Wiley Online Library
Tacrine is a drug used in the treatment of Alzheimer's disease as a cognitive enhancer and
inhibitor of the enzyme acetylcholinesterase (AChE). However, its clinical application has …

Application of marine natural products against Alzheimer's disease: past, present and future

D Hu, Y Jin, X Hou, Y Zhu, D Chen, J Tai, Q Chen… - Marine Drugs, 2023 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative disease, is one of the most intractable
illnesses which affects the elderly. Clinically manifested as various impairments in memory …

Encapsulation of bryostatin-1 by targeted exosomes enhances remyelination and neuroprotection effects in the cuprizone-induced demyelinating animal model of …

XY Wu, BY Liao, D Xiao, WC Wu, Y Xiao… - Biomaterials …, 2022 - pubs.rsc.org
Demyelination is a critical neurological disease, and there is still a lack of effective treatment
methods. In the past two decades, stem cells have emerged as a novel therapeutic effector …