Effects of exercise on anxiety and depression disorders: review of meta-analyses and neurobiological mechanisms
Anxiety and depression are the most frequently diagnosed psychological diseases showing
a high co-morbidity. They have a severe impact on the lives of the persons concerned. Many …
a high co-morbidity. They have a severe impact on the lives of the persons concerned. Many …
Molecular mechanisms underlying cardiac adaptation to exercise
Exercise elicits coordinated multi-organ responses including skeletal muscle, vasculature,
heart, and lung. In the short term, the output of the heart increases to meet the demand of …
heart, and lung. In the short term, the output of the heart increases to meet the demand of …
Long-term exercise from adolescence to adulthood reduces anxiety-and depression-like behaviors following maternal immune activation in offspring
S Rahimi, M Peeri, MA Azarbayjani, L Anoosheh… - Physiology & …, 2020 - Elsevier
Maternal immune activation is an environmental risk factor for the development of
neuropsychiatric disorders such as anxiety and depression later in life. There is an urgent …
neuropsychiatric disorders such as anxiety and depression later in life. There is an urgent …
Potential therapeutic uses of BDNF in neurological and psychiatric disorders
AH Nagahara, MH Tuszynski - Nature reviews Drug discovery, 2011 - nature.com
The growth factor brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …
The exercise-glucocorticoid paradox: How exercise is beneficial to cognition, mood, and the brain while increasing glucocorticoid levels
C Chen, S Nakagawa, Y An, K Ito, Y Kitaichi… - Frontiers in …, 2017 - Elsevier
Exercise is known to have beneficial effects on cognition, mood, and the brain. However,
exercise also activates the hypothalamic–pituitary–adrenal axis and increases levels of the …
exercise also activates the hypothalamic–pituitary–adrenal axis and increases levels of the …
A runner's high depends on cannabinoid receptors in mice
Exercise is rewarding, and long-distance runners have described a runner's high as a
sudden pleasant feeling of euphoria, anxiolysis, sedation, and analgesia. A popular belief …
sudden pleasant feeling of euphoria, anxiolysis, sedation, and analgesia. A popular belief …
Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin
Adiponectin (ADN) is an adipocyte-secreted protein with insulin-sensitizing, antidiabetic,
antiinflammatory, and antiatherogenic properties. Evidence is also accumulating that ADN …
antiinflammatory, and antiatherogenic properties. Evidence is also accumulating that ADN …
Efficacy and Mechanisms of Aerobic Exercise on Cancer Initiation, Progression, and Metastasis: A Critical Systematic Review of In Vivo Preclinical Data
KA Ashcraft, RM Peace, AS Betof, MW Dewhirst… - Cancer research, 2016 - AACR
A major objective of the emerging field of exercise–oncology research is to determine the
efficacy of, and biological mechanisms by which, aerobic exercise affects cancer incidence …
efficacy of, and biological mechanisms by which, aerobic exercise affects cancer incidence …
The muscle-brain axis and neurodegenerative diseases: the key role of mitochondria in exercise-induced neuroprotection
Regular exercise is associated with pronounced health benefits. The molecular processes
involved in physiological adaptations to exercise are best understood in skeletal muscle …
involved in physiological adaptations to exercise are best understood in skeletal muscle …
Effects of voluntary and involuntary exercise on cognitive functions, and VEGF and BDNF levels in adolescent rats
Regular treadmill running during adolescence improves learning and memory in rats.
During adolescence, the baseline level of stress is thought to be greater than during other …
During adolescence, the baseline level of stress is thought to be greater than during other …