[HTML][HTML] A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophrenia

AJ McGuinness, JA Davis, SL Dawson… - Molecular …, 2022 - nature.com
The emerging understanding of gut microbiota as 'metabolic machinery'influencing many
aspects of physiology has gained substantial attention in the field of psychiatry. This is …

Multiple roles of short-chain fatty acids in Alzheimer disease

H Chen, L Meng, L Shen - Nutrition, 2022 - Elsevier
Alzheimer disease (AD) is the most common form of neurodegenerative disease in older
adults and has a complicated etiology. Recently, the roles of short-chain fatty acids (SCFAs) …

Gut microbiome composition may be an indicator of preclinical Alzheimer's disease

AL Ferreiro, JH Choi, J Ryou, EP Newcomer… - Science translational …, 2023 - science.org
Alzheimer's disease (AD) pathology is thought to progress from normal cognition through
preclinical disease and ultimately to symptomatic AD with cognitive impairment. Recent work …

Gut microbiota regulates blood‐cerebrospinal fluid barrier function and Aβ pathology

J Xie, A Bruggeman, C De Nolf… - The EMBO …, 2023 - embopress.org
Accumulating evidence indicates that gut microbiota dysbiosis is associated with increased
blood–brain barrier (BBB) permeability and contributes to Alzheimer's disease (AD) …

Dietary fiber modulates the release of gut bacterial products preventing cognitive decline in an Alzheimer's mouse model

D Cuervo-Zanatta, T Syeda, V Sánchez-Valle… - Cellular and molecular …, 2023 - Springer
Fiber intake is associated with a lower risk for Alzheimer´ s disease (AD) in older adults.
Intake of plant-based diets rich in soluble fiber promotes the production of short-chain fatty …

[HTML][HTML] Memorable food: fighting age-related neurodegeneration by precision nutrition

M Milošević, A Arsić, Z Cvetković, V Vučić - Frontiers in Nutrition, 2021 - frontiersin.org
Healthcare systems worldwide are seriously challenged by a rising prevalence of
neurodegenerative diseases (NDDs), which mostly, but not exclusively, affect the ever …

[HTML][HTML] Current understanding of the Alzheimer's disease-associated microbiome and therapeutic strategies

D Seo, DM Holtzman - Experimental & Molecular Medicine, 2024 - nature.com
Alzheimer's disease (AD) is a fatal progressive neurodegenerative disease. Despite
tremendous research efforts to understand this complex disease, the exact pathophysiology …

Targeting epigenetics: a novel promise for Alzheimer's disease treatment

D Jeremic, L Jiménez-Díaz, JD Navarro-López - Ageing Research Reviews, 2023 - Elsevier
So far, the search for a cure for Alzheimer Disease (AD) has been unsuccessful. The only
approved drugs attenuate some symptoms, but do not halt the progress of this disease …

[HTML][HTML] Reducing branched-chain amino acids improves cardiac stress response in mice by decreasing histone H3K23 propionylation

Z Yang, M He, J Austin, D Sayed… - The Journal of Clinical …, 2023 - Am Soc Clin Investig
Identification of branched-chain amino acid (BCAA) oxidation enzymes in the nucleus led us
to predict that they are a source of the propionyl-CoA that is utilized for histone …

[HTML][HTML] Exploration of the gut–brain axis through metabolomics identifies serum propionic acid associated with higher cognitive decline in older persons

J Neuffer, R González-Domínguez, S Lefèvre-Arbogast… - Nutrients, 2022 - mdpi.com
The gut microbiome is involved in nutrient metabolism and produces metabolites that, via
the gut–brain axis, signal to the brain and influence cognition. Human studies have so far …