Radiotheranostics in oncology: making precision medicine possible

EO Aboagye, TD Barwick… - CA: A Cancer Journal for …, 2023 - Wiley Online Library
A quintessential setting for precision medicine, theranostics refers to a rapidly evolving field
of medicine in which disease is diagnosed followed by treatment of disease‐positive …

CXCL12/CXCR4 axis in the microenvironment of solid tumors: A critical mediator of metastasis

K Mortezaee - Life sciences, 2020 - Elsevier
Tumors are dynamic tissue masses, so requiring continuous exposure to the host cells,
nurturing them into pave a path for tumor growth and metastasis. CXC chemokine ligand 12 …

PET imaging in patients with brain metastasis—report of the RANO/PET group

N Galldiks, KJ Langen, NL Albert… - Neuro …, 2019 - academic.oup.com
Brain metastases (BM) from extracranial cancer are associated with significant morbidity and
mortality. Effective local treatment options are stereotactic radiotherapy, including …

Design and challenges of radiopharmaceuticals

K Vermeulen, M Vandamme, G Bormans… - Seminars in nuclear …, 2019 - Elsevier
This review describes general concepts with regard to radiopharmaceuticals for diagnostic
or therapeutic applications that help to understand the specific challenges encountered …

[HTML][HTML] Targeting CXCR4 in AML and all

D Cancilla, MP Rettig, JF DiPersio - Frontiers in oncology, 2020 - frontiersin.org
The interaction of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL)
blasts with the bone marrow microenvironment regulates self-renewal, growth signaling, as …

Radiolabeled peptides and antibodies in medicine

P Kręcisz, K Czarnecka, L Królicki… - Bioconjugate …, 2020 - ACS Publications
Radiolabeled peptides are a relatively new, very specific radiotracer group, which is still
expanding. This group is very diverse in terms of peptide size. It contains very small …

[HTML][HTML] Kirenol: a potential natural lead molecule for a new drug design, development, and therapy for inflammation

NN Nasir, M Sekar, S Fuloria, SH Gan, NNIM Rani… - Molecules, 2022 - mdpi.com
Kirenol, a potential natural diterpenoid molecule, is mainly found in Sigesbeckia species.
Kirenol has received a lot of interest in recent years due to its wide range of pharmacological …

[PDF][PDF] The tumor microenvironment and immunotherapy in prostate and bladder cancer

SS Nair, R Weil, Z Dovey, A Davis, AK Tewari - Urologic Clinics of North …, 2020 - Elsevier
Acknowledgements: The authors wish to thank Sima Rabinowitz, SR for editorial assistance.
The authors wish to acknowledge funding support from the Deane Prostate Health, ISMMS …

Improved primary staging of marginal-zone lymphoma by addition of CXCR4-directed PET/CT

J Duell, F Krummenast, A Schirbel… - Journal of Nuclear …, 2021 - Soc Nuclear Med
PET/CT with 18F-FDG is an integral component in the primary staging of most lymphomas.
However, its utility is limited in marginal-zone lymphoma (MZL) because of inconsistent 18F …

[HTML][HTML] Clinical advances and perspectives in targeted radionuclide therapy

N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …