A systematic review and meta-analysis of supramarginal resection versus gross total resection in glioblastoma: can we enhance progression-free survival time and …

J Wach, M Vychopen, A Kuehnapfel, C Seidel… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma tumor cells are frequently found in areas distant from
conventional imaging abnormalities. These cells are thought to play a role in tumor …

Neural stem cell delivery of an oncolytic adenovirus in newly diagnosed malignant glioma: a first-in-human, phase 1, dose-escalation trial

J Fares, AU Ahmed, IV Ulasov, AM Sonabend… - The Lancet …, 2021 - thelancet.com
Background Malignant glioma is the most common and lethal primary brain tumour, with
dismal survival rates and no effective treatment. We examined the safety and activity of NSC …

Supramarginal resection for glioblastoma: it is time to set boundaries! A critical review on a hot topic

F Guerrini, E Roca, G Spena - Brain Sciences, 2022 - mdpi.com
Glioblastoma are the most common primary malignant brain tumors with a highly infiltrative
behavior. The extent of resection of the enhancing component has been shown to be …

IDH–wild-type glioblastoma cell density and infiltration distribution influence on supramarginal resection and its impact on overall survival: a mathematical model

S Tripathi, T Vivas-Buitrago, RA Domingo… - Journal of …, 2021 - thejns.org
OBJECTIVE Recent studies have proposed resection of the T2 FLAIR hyperintensity beyond
the T1 contrast enhancement (supramarginal resection [SMR]) for IDH–wild-type …

Surgical treatment of glioblastoma: State-of-the-art and future trends

AHA Sales, J Beck, O Schnell, C Fung, B Meyer… - Journal of Clinical …, 2022 - mdpi.com
Glioblastoma (GBM) is a highly aggressive disease and is associated with poor prognosis
despite treatment advances in recent years. Surgical resection of tumor remains the main …

Nitric oxide synthase inhibitors as potential therapeutic agents for gliomas: A systematic review

MA Merenzon, EH Arias, S Bhatia, AH Shah… - Nitric Oxide, 2023 - Elsevier
Introduction Gliomas represent the most prevalent form of brain tumors, among which
glioblastomas are the most malignant subtype. Despite advances in comprehending their …

Radical supramaximal resection for newly diagnosed left-sided eloquent glioblastoma: safety and improved survival over gross-total resection

L Di, AH Shah, A Mahavadi, DG Eichberg… - Journal of …, 2022 - thejns.org
OBJECTIVE Supramaximal resection (SMR) has arisen as a possible surrogate to gross-
total resection (GTR) to improve survival in newly diagnosed glioblastoma (nGBM) …

Regulation of cancer stem cells and immunotherapy of glioblastoma

А Kosianova, O Pak… - Biomedical …, 2023 - spandidos-publications.com
Glioblastoma (GB) is one of the most adverse diagnoses in oncology. Complex current
treatment results in a median survival of 15 months. Resistance to treatment is associated …

Lobectomy versus gross total resection for glioblastoma multiforme: A systematic review and individual-participant data meta-analysis

Y Zheng, SE Saffari, DCY Low, X Lin, JRX Ker… - Journal of Clinical …, 2023 - Elsevier
Overall survival (OS) for glioblastoma multiforme (GBM) has a known association with the
extent of tumor resection with gross total resection (GTR) typically considered as the upper …

Supratotal resection of gliomas with awake brain mapping: maximal tumor resection preserving motor, language, and neurocognitive functions

K Motomura, F Ohka, K Aoki, R Saito - Frontiers in Neurology, 2022 - frontiersin.org
Gliomas are a category of infiltrating glial neoplasms that are often located within or near the
eloquent areas involved in motor, language, and neurocognitive functions. Surgical …