The extracellular matrix (ECM) constitutes a highly dynamic three-dimensional structural
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …

Leukocyte migration into tissues depends on the activity of chemokines that form
concentration gradients to guide leukocytes to a specific site. Interaction of chemokines with …

Heparan sulfate proteoglycans consist of a small family of proteins decorated with one or
more covalently attached heparan sulfate glycosaminoglycan chains. These chains have …

Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular
matrix in all the animal species. This review will focus on the structural characteristics of the …

Glycosaminoglycans (GAGs) play a crucial role in tissue homeostasis by regulating the
activity and diffusion of bioactive molecules. Incorporating GAGs into biomaterials has …

By targeting cells that provide protection against infection, HIV-1 causes acquired
immunodeficiency syndrome. Infection starts when gp120, the viral envelope glycoprotein …

Laminin 332, composed of the α3, β3 and γ2 chains, is an epithelial-basement membrane
specific laminin variant. Its main role in normal tissues is the maintenance of epithelial …

Human immunodeficiency virus (HIV) attachment to host cells is a multi-step process that
involves interaction of the viral envelope gp120 with the primary receptor CD4 and …

Techniques involving solid supports have played crucial roles in the development of
genomics, proteomics, and in molecular biology in general. Simularly, methods for …

Epitope mapping is an important step in characterizing antibodies that bind a potential
therapeutic target. By selection from a phage Ab library, one might obtain a few hundred Abs …