Neglected tropical diseases (NTDs) constitute a group of infectious diseases prevalent in
countries with tropical and subtropical climate that affect the poorest individuals and produce …

The objective of this work was to access thymol-excipient compatibility using an alternative
protocol of mixture design subsidizing the development of nanostructures lipid carriers …

The analysed substances, procaine and benzocaine, are two anaesthetic agents currently
being administered in tablet form, also in the topical (cream, gel, balm) and injectable …

The aim of this work was to evaluate the compatibility of (+)-catechin (CA) and excipients
commonly used to prepare micro and nanoemulsions using thermal analysis along with …

Carvedilol (CARV) is a widely used non-selective β-blocker, which has shown low
bioavailability after oral administration (20%) due to its low water solubility and intense first …

Chagas disease is a neglected endemic disease prevalent in Latin American countries,
affecting around 8 million people. The first-line treatment, benznidazole (BNZ), is effective in …

Detection of incompatibility between an active pharmaceutical ingredient (API) and
excipients, including the selection of the most biopharmaceutical advantageous excipients is …

Recent studies have shown that the antifungal itraconazole (ITZ), when in associations with
benznidazole (BNZ), is a potential treatment for Chagas disease. Therefore, the objective of …

Complexation of benznidazole (BZL), a drug of choice for the treatment of Chagas'
neglected disease, with cyclodextrin (CD) derivatives was analyzed by solid-state NMR. 13 …

The compatibility of an amphiphilic pH-sensitive polymer (docosahexaenoic acid–histidine–
lysine, DHA–HisXLys10) and hydrophobic drug (doxorubicin, DOX) was investigated using …