Microfluidics in High-Throughput Drug Screening: Organ-on-a-Chip and C. elegans-Based Innovations

S Yoon, D Kilicarslan You, U Jeong, M Lee, E Kim… - Biosensors, 2024 - mdpi.com
The development of therapeutic interventions for diseases necessitates a crucial step known
as drug screening, wherein potential substances with medicinal properties are rigorously …

Tunable resins with PDMS-like elastic modulus for stereolithographic 3D-printing of multimaterial microfluidic actuators

A Ahmadianyazdi, IJ Miller, A Folch - Lab on a Chip, 2023 - pubs.rsc.org
Stereolithographic 3D-printing (SLA) permits facile fabrication of high-precision microfluidic
and lab-on-a-chip devices. SLA photopolymers often yield parts with low mechanical …

Validation of HepG2/C3A cell cultures in cyclic olefin copolymer based microfluidic bioreactors

L Etxeberria, T Messelmani, JH Badiola, A Llobera… - Polymers, 2022 - mdpi.com
Organ-on-chip (OoC) technology is one of the most promising in vitro tools to replace the
traditional animal experiment-based paradigms of risk assessment. However, the use of …

Bioprinted Multi‐Composition Array Mimicking Tumor Microenvironments to Evaluate Drug Efficacy with Multivariable Analysis

G Lee, SJ Kim, JK Park - Advanced Healthcare Materials, 2024 - Wiley Online Library
Current organ‐on‐a‐chip technologies confront limitations in effectively recapitulating the
intricate in vivo microenvironments and accommodating diverse experimental conditions on …

Solvent-Resistant Perfluoropolyether Microfluidic Devices with Microfibrous Channels for the Production of Poly (ε-caprolactone) Microspheres Containing …

DH Oh, I Choi, YH Ryu, GY Ahn, TK Ryu… - ACS Applied Polymer …, 2023 - ACS Publications
A microfluidic device with microfibrous channels was prepared using perfluoropolyether
(PFPE) and poly (ethylene glycol) diacrylate (PEG-DA). PFPE was chosen as a major …

[PDF][PDF] Validation of HepG2/C3A Cell Cultures in Cyclic Olefin Copolymer Based Microfluidic Bioreactors. Polymers 2022, 14, 4478

L Etxeberria, T Messelmani, JH Badiola, A Llobera… - 2022 - hal.utc.fr
Organ-on-chip (OoC) technology is one of the most promising in vitro tools to replace the
traditional animal experiment-based paradigms of risk assessment. However, the use of …