There has long been an appreciation that cerebral blood flow is modulated to ensure
adequate cerebral oxygen delivery in the face of systemic hypoxaemia. There is increasing …

Objective: In this study we have used 15 O positron emission tomography, brain tissue
oxygen monitoring, and cerebral microdialysis to assess the effects of cerebral perfusion …

Introduction Posttraumatic brain ischemia or hypoxia is a major potential cause of secondary
injury that may lead to poor outcome. Avoidance, or amelioration, of this secondary injury …

OBJECTIVE: A prospective observational study was conducted to investigate whether
episodes of ischemia are detected by continuous cerebral monitoring and whether such …

Measuring brain tissue oxygenation is now possible due to major advances in the technical
development of Clark-electrodes and fiberoptic systems. However, to make this technique …

Object. The aim of this study was to investigate potential episodes of cerebral ischemia
during surgery for large and complicated aneurysms, by examining the effects of arterial …

Object. Brain tissue acidosis is known to mediate neuronal death. Therefore the authors
measured the main parameters of cerebral acid—base homeostasis, as well as their …

OBJECTIVE: Most physicians rely on conventional treatment targets for intracranial
pressure, cerebral perfusion pressure, systemic oxygenation, and hemoglobin to direct …

Object. Temporary arterial occlusion (TAO) during aneurysm surgery carries the risk of
ischemic sequelae. Because monitoring of regional cerebral blood flow (rCBF) may limit …

OBJECTIVE: To introduce rapid-sampling microdialysis for the early detection of adverse
metabolic changes in tissue at risk during aneurysm surgery. METHODS: A microdialysis …