Serratia infections: from military experiments to current practice

SD Mahlen - Clinical microbiology reviews, 2011 - Am Soc Microbiol
Serratia species, in particular Serratia marcescens, are significant human pathogens. S.
marcescens has a long and interesting taxonomic, medical experimentation, military …

Friend or foe? A review of the mechanisms that drive Serratia towards diverse lifestyles

LM Petersen, LS Tisa - Canadian journal of microbiology, 2013 - cdnsciencepub.com
Found widespread around the globe, Serratia are Gram-negative bacteria capable of
thriving in a diverse number of environments that include water, soil, and the digestive tracts …

A Legionella Effector Disrupts Host Cytoskeletal Structure by Cleaving Actin

Y Liu, W Zhu, Y Tan, ES Nakayasu, CJ Staiger… - PLoS …, 2017 - journals.plos.org
Legionella pneumophila, the etiological agent of Legionnaires' disease, replicates
intracellularly in protozoan and human hosts. Successful colonization and replication of this …

Porphyromonas gingivalis influences actin degradation within epithelial cells during invasion and apoptosis

JA Kinane, MR Benakanakere, J Zhao… - Cellular …, 2012 - Wiley Online Library
Porphyromonas gingivalis, a Gram‐negative oral pathogen, has been shown to induce
apoptosis in human gingival epithelial cells, yet the underlining cellular mechanisms …

NMR structure of emfourin, a novel protein metalloprotease inhibitor: Insights into the mechanism of action

TN Bozin, IM Berdyshev, KN Chukhontseva… - Journal of Biological …, 2023 - ASBMB
Emfourin (M4in) is a protein metalloprotease inhibitor recently discovered in the bacterium
Serratia proteamaculans and the prototype of a new family of protein protease inhibitors with …

Identification of SlpB, a cytotoxic protease from Serratia marcescens

RMQ Shanks, NA Stella, KM Hunt… - Infection and …, 2015 - Am Soc Microbiol
The Gram-negative bacterium and opportunistic pathogen Serratia marcescens causes
ocular infections in healthy individuals. Secreted protease activity was characterized from 44 …

Involvement of Lipid Rafts in the Invasion of Opportunistic Bacteria Serratia into Eukaryotic Cells

Y Berson, S Khaitlina, O Tsaplina - International Journal of Molecular …, 2023 - mdpi.com
Cell membrane rafts form signaling platforms on the cell surface, controlling numerous
protein–protein and lipid–protein interactions. Bacteria invading eukaryotic cells trigger cell …

Cleavage of the outer membrane protein OmpX by protealysin regulates Serratia proteamaculans invasion

O Tsaplina, I Demidyuk, T Artamonova… - FEBS …, 2020 - Wiley Online Library
Protealysin is a thermolysin‐like protease of Serratia proteamaculans capable of specifically
cleaving actin, which correlates with the invasive activity of these bacteria. Here, we show …

Protealysin targets the bacterial housekeeping proteins FtsZ and RecA

O Tsaplina, S Khaitlina, K Chukhontseva… - International Journal of …, 2022 - mdpi.com
Serratia proteamaculans synthesizes the intracellular metalloprotease protealysin. This work
was aimed at searching for bacterial substrates of protealysin among the proteins …

Bacterial Actin-Specific Endoproteases Grimelysin and Protealysin as Virulence Factors Contributing to the Invasive Activities of Serratia

S Khaitlina, E Bozhokina, O Tsaplina… - International Journal of …, 2020 - mdpi.com
The article reviews the discovery, properties and functional activities of new bacterial
enzymes, proteases grimelysin (ECP 32) of Serratia grimesii and protealysin of Serratia …