Heat shock proteins and cancer

J Wu, T Liu, Z Rios, Q Mei, X Lin, S Cao - Trends in pharmacological …, 2017 - cell.com
Heat shock proteins (HSPs) constitute a large family of proteins involved in protein folding
and maturation whose expression is induced by heat shock or other stressors. The major …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

The mitochondrial unfolded protein response (UPRmt): shielding against toxicity to mitochondria in cancer

JR Inigo, D Chandra - Journal of hematology & oncology, 2022 - Springer
Mitochondria are essential for tumor growth and progression. However, the heavy demand
for mitochondrial activity in cancer leads to increased production of mitochondrial reactive …

Heat shock proteins promote cancer: it's a protection racket

SK Calderwood, J Gong - Trends in biochemical sciences, 2016 - cell.com
Heat shock proteins (HSP) are expressed at high levels in cancer and form a fostering
environment that is essential for tumor development. Here, we review the recent data in this …

[HTML][HTML] Exosomes as potential sources of biomarkers in colorectal cancer

Y Xiao, J Zhong, B Zhong, J Huang, L Jiang, Y Jiang… - Cancer letters, 2020 - Elsevier
Colorectal cancer (CRC), a common malignancy, is among the leading causes of cancer-
related deaths worldwide. Developing novel biomarkers is an important public health …

Extracellular vesicles in liquid biopsies as biomarkers for solid tumors

B Irmer, S Chandrabalan, L Maas, A Bleckmann… - Cancers, 2023 - mdpi.com
Simple Summary During the past decade, liquid biopsy-related publications have increased
exponentially, demonstrating the great potential of screening body fluids for diagnosis …

Evidence-based clinical use of nanoscale extracellular vesicles in nanomedicine

S Fais, L O'Driscoll, FE Borras, E Buzas, G Camussi… - 2016 - ACS Publications
Recent research has demonstrated that all body fluids assessed contain substantial
amounts of vesicles that range in size from 30 to 1000 nm and that are surrounded by …

[HTML][HTML] Recent advances in heat shock proteins in cancer diagnosis, prognosis, metabolism and treatment

S Yang, H Xiao, L Cao - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Heat shock proteins (HSPs) are a group of proteins, also known as molecular chaperones,
which participate in protein folding and maturation in response to stresses or high …

[HTML][HTML] Extracellular heat shock proteins and cancer: New perspectives

Z Albakova, MKS Siam, PK Sacitharan… - Translational …, 2021 - Elsevier
Heat shock proteins (HSPs) are a large family of molecular chaperones aberrantly
expressed in cancer. The expression of HSPs in tumor cells has been shown to be …

Biomarkers in prostate cancer diagnosis: from current knowledge to the role of metabolomics and exosomes

S Salciccia, AL Capriotti, A Laganà, S Fais… - International journal of …, 2021 - mdpi.com
Early detection of prostate cancer (PC) is largely carried out using assessment of prostate-
specific antigen (PSA) level; yet it cannot reliably discriminate between benign pathologies …