Immunotherapy for cancer is a rapidly developing treatment that modifies the immune
system and enhances the antitumor immune response. B7-H3 (CD276), a member of the B7 …

Mast cells (MCs) are tissue-resident immune cells that are important players in diseases
associated with chronic inflammation such as cancer. Since MCs can infiltrate solid tumors …

Hypoxia and high accumulation of lactic acid in the tumor microenvironment provide fertile
soil for tumor development, maintenance and metastasis. Herein, we developed a calcium …

Angiogenesis is the process of generating new blood vessels from pre-existing vasculature.
Under normal conditions, this process is delicately controlled by pro-angiogenic and anti …

Vascular endothelial growth factors (VEGFs) are the key regulators of vasculogenesis in
normal and oncological development. VEGF-A is the most studied angiogenic factor …

The immune checkpoint B7-H3 (CD276), a member of the B7 family with immunoregulatory
properties, has been identified recently as a novel target for immunotherapy for refractory …

The process of angiogenesis is well described for its potential role in the development of
normal ovaries, and physiological functions as well as in the initiation, progression, and …

In 1971, Folkman proposed that tumors could be limited to very small sizes by blocking
angiogenesis. Angiogenesis is the generation of new blood vessels from pre-existing …

Oncolytic viruses (OVs) are emerging as potential treatment options for cancer. Natural and
genetically engineered viruses exhibit various antitumor mechanisms. OVs act by direct …

Angiogenesis is an essential process for tumor development. Owing to the imbalance
between pro-and anti-angiogenic factors, the tumor vasculature possesses the …