Techniques to assess bone ultrastructure organization: orientation and arrangement of mineralized collagen fibrils
M Georgiadis, R Müller… - Journal of the Royal …, 2016 - royalsocietypublishing.org
Bone's remarkable mechanical properties are a result of its hierarchical structure. The
mineralized collagen fibrils, made up of collagen fibrils and crystal platelets, are bone's …
mineralized collagen fibrils, made up of collagen fibrils and crystal platelets, are bone's …
Next-generation imaging of the skeletal system and its blood supply
Bone is organized in a hierarchical 3D architecture. Traditionally, analysis of the skeletal
system was based on bone mass assessment by radiographic methods or on the …
system was based on bone mass assessment by radiographic methods or on the …
Quantifying the osteocyte network in the human skeleton
PR Buenzli, NA Sims - Bone, 2015 - Elsevier
Osteocytes form an extensive cellular network throughout the hard tissue matrix of the
skeleton, which is known to regulate skeletal structure. However due to limitations in …
skeleton, which is known to regulate skeletal structure. However due to limitations in …
The mechanoresponse of bone is closely related to the osteocyte lacunocanalicular network architecture
AF Van Tol, V Schemenz… - Proceedings of the …, 2020 - National Acad Sciences
Organisms rely on mechanosensing mechanisms to adapt to changes in their mechanical
environment. Fluid-filled network structures not only ensure efficient transport but can also …
environment. Fluid-filled network structures not only ensure efficient transport but can also …
An organoid for woven bone
Bone formation (osteogenesis) is a complex process in which cellular differentiation and the
generation of a mineralized organic matrix are synchronized to produce a hybrid …
generation of a mineralized organic matrix are synchronized to produce a hybrid …
[HTML][HTML] Characterization and distribution of mechanically competent mineralized tissue in micropores of β-tricalcium phosphate bone substitutes
Although bone formation around and within implants has been intensively studied, the role
of pores and pore geometry is still debated. Notwithstanding studies reporting the formation …
of pores and pore geometry is still debated. Notwithstanding studies reporting the formation …
[HTML][HTML] Osteoporosis and Covid-19: Detected similarities in bone lacunar-level alterations via combined AI and advanced synchrotron testing
While advanced imaging strategies have improved the diagnosis of bone-related
pathologies, early signs of bone alterations remain difficult to detect. The Covid-19 …
pathologies, early signs of bone alterations remain difficult to detect. The Covid-19 …
Long‐term immobilization in elderly females causes a specific pattern of cortical bone and osteocyte deterioration different from postmenopausal osteoporosis
Immobilization as a result of long‐term bed rest can lead to gradual bone loss. Because of
their distribution throughout the bone matrix and remarkable interconnectivity, osteocytes …
their distribution throughout the bone matrix and remarkable interconnectivity, osteocytes …
Synchrotron X-ray studies of the structural and functional hierarchies in mineralised human dental enamel: A state-of-the-art review
C Besnard, A Marie, S Sasidharan, RA Harper… - Dentistry Journal, 2023 - mdpi.com
Hard dental tissues possess a complex hierarchical structure that is particularly evident in
enamel, the most mineralised substance in the human body. Its complex and interlinked …
enamel, the most mineralised substance in the human body. Its complex and interlinked …
Micro-and nano-CT for the study of bone ultrastructure
Micro-computed tomography (micro-CT)—a version of X-ray CT operating at high spatial
resolution—has had a considerable success for the investigation of trabecular bone micro …
resolution—has had a considerable success for the investigation of trabecular bone micro …