The role of melatonin on doxorubicin-induced cardiotoxicity: a systematic review

M Najafi, MRH Shayesteh, K Mortezaee, B Farhood… - Life sciences, 2020 - Elsevier
Purpose Doxorubicin, as an effective chemotherapeutic drug, is commonly used for
combating various solid and hematological tumors. However, doxorubicin-induced …

Melatonin, an inhibitory agent in breast cancer

E Nooshinfar, A Safaroghli-Azar, D Bashash… - Breast Cancer, 2017 - Springer
Background The heterogeneous nature of breast cancer makes it one of the most
challenging cancers to treat. Due to the stimulatory effect of estrogen in mammary cancer …

Manufacturing drug co-loaded liposomal formulations targeting breast cancer: Influence of preparative method on liposomes characteristics and in vitro toxicity

L Gkionis, RA Campbell, H Aojula, LK Harris… - International journal of …, 2020 - Elsevier
Developing more efficient manufacturing methods for nano therapeutic systems is becoming
important, not only to better control their physico-chemical characteristics and therapeutic …

Optimization and in-vitro/in-vivo evaluation of doxorubicin-loaded chitosan-alginate nanoparticles using a melanoma mouse model

K Yoncheva, M Merino, A Shenol, NT Daskalov… - International journal of …, 2019 - Elsevier
The present study evaluates the potential of encapsulated doxorubicin to reduce both the
viability of melanoma cells and the tumor growth in a mouse melanoma model. The …

Breakthroughs in modern cancer therapy and elusive cardiotoxicity: Critical research‐practice gaps, challenges, and insights

PP Zheng, J Li, JM Kros - Medicinal research reviews, 2018 - Wiley Online Library
To date, five cancer treatment modalities have been defined. The three traditional modalities
of cancer treatment are surgery, radiotherapy, and conventional chemotherapy, and the two …

[HTML][HTML] Microfluidic-assisted fabrication of phosphatidylcholine-based liposomes for controlled drug delivery of chemotherapeutics

L Gkionis, H Aojula, LK Harris, A Tirella - International journal of …, 2021 - Elsevier
Microfluidic enables precise control over the continuous mixing of fluid phases at the
micrometre scale, aiming to optimize the processing parameters and to facilitate scale-up …

A cross-talk about radioresistance in lung cancer—How to improve radiosensitivity according to Chinese medicine and medicaments that commonly occur in …

P Nowak, I Bil-Lula, M Śliwińska-Mossoń - International Journal of …, 2023 - mdpi.com
Lung cancer is one of the most common cancers in the population and is characterized by
non-specific symptoms that delay the diagnosis and reduce the effectiveness of oncological …

[HTML][HTML] The role of circadian clocks in cancer: Mechanisms and clinical implications

H Liu, Y Liu, R Hai, W Liao, X Luo - Genes & Diseases, 2023 - Elsevier
Circadian rhythm refers to the inherent 24-h cycle oscillation of biochemical, physiological
and behavioral functions, which is almost universal in eukaryotes. At least 14 core clock …

A new dawn for the use of thiazolidinediones in cancer therapy

H Joshi, T Pal, CS Ramaa - Expert opinion on investigational drugs, 2014 - Taylor & Francis
Introduction: The thiazolidinedione (TZD) class of PPAR-γ ligands is predominantly known
for its insulin sensitization activity. Unfortunately, these drugs have discernible side effects at …

Anticancer activity and molecular mechanisms of α‐conidendrin, a polyphenolic compound present in Taxus yunnanensis, on human breast cancer cell lines

K Hafezi, AA Hemmati, H Abbaszadeh… - Phytotherapy …, 2020 - Wiley Online Library
α‐Conidendrin is a polyphenolic compound found mainly in Taxus yunnanensis, as the
source of chemotherapy drug paclitaxel, which has been used in traditional medicine for …