Protective effects of flavonoids against Alzheimer's disease: pathological hypothesis, potential targets, and structure–activity relationship
J Li, M Sun, X Cui, C Li - International Journal of Molecular Sciences, 2022 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease with high morbidity and mortality,
for which there is no available cure. Currently, it is generally believed that AD is a disease …
for which there is no available cure. Currently, it is generally believed that AD is a disease …
Update on new trends and progress of natural active ingredients in the intervention of Alzheimer's disease, based on understanding of traditional Chinese and …
W Li, Y Rang, H Liu, C Liu - Phytotherapy Research, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the major neurological disorders causing death in the
elderly worldwide. As a neurodegenerative disease that is difficult to prevent and cure, the …
elderly worldwide. As a neurodegenerative disease that is difficult to prevent and cure, the …
Novel Mannich bases derived from 1, 2, 4-triazoles: Design, synthesis, characterization, and glutathione S-transferase inhibition properties investigations
The reaction of variously substituted 1, 2, 4-triazole derivatives with morpholine and
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …
formaldehyde represents an efficient and easy-to-set synthetic entry toward heterocyclic N …
Phytochemical Investigation of Hypericum heterophyllum Flowers: LC-ESI-MS/MS Analysis, Total Phenolic and Flavonoid Contents, Antioxidant Activity
R Erenler, C Yaman, lbrahim Demirtas… - The Natural Products …, 2023 - benthamdirect.com
Background: Hypericum heterophyllum has been used as a traditional medicine and
includes significant bioactive compounds. Objective: To quantitatively determine the …
includes significant bioactive compounds. Objective: To quantitatively determine the …
Phytochemical analysis and biological activity of Corchorus olitorius L.: Quantitative analysis of bioactive compounds by LC–MS/MS, antibacterial, enzyme inhibition …
Introduction Corchorus olitorius L. is a significant plant in folk medicine, therefore, research
on phytochemistry with biological activity may reveal its potential use in drug development …
on phytochemistry with biological activity may reveal its potential use in drug development …
Combination of metabolomics and network pharmacology analysis to decipher the mechanisms of total flavonoids of Litchi seed against prostate cancer
D Cui, Z Luo, X Liu, X Chen, Q Zhang… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives To explore the underlying mechanism of total flavonoids of Litchi seed (TFLS) in
treating prostate cancer (PCa). Methods Cell Counting Kit-8 (CCK-8), EdU incorporation …
treating prostate cancer (PCa). Methods Cell Counting Kit-8 (CCK-8), EdU incorporation …
Synthesis, characterization of novel mannich bases and their acetylcholinesterase and glutathione S-transferase inhibitory properties: An in vitro and in silico …
Abstract In this study, 4-((3, 4-Dimethoxybenzylidene) amino)-5-alkyl (aryl)-2, 4-dihydro-3H-
1, 2, 4-triazol-3-ones (4a-g) reacted with formaldehyde and 2, 6-dimethylmorpholine to …
1, 2, 4-triazol-3-ones (4a-g) reacted with formaldehyde and 2, 6-dimethylmorpholine to …
Analysis of bioactive compounds using LC–ESI–MS/MS, cytotoxic, antimicrobial effects, and enzyme activities from Cyclotrichium origanifolium
Cyclotrichium origanifolium is a medicinal plant belonging to the Lamiaceae family. In this
study, phenolic content analysis, antimicrobial effects, and cytotoxic effects of extracts of C …
study, phenolic content analysis, antimicrobial effects, and cytotoxic effects of extracts of C …
Synthesis of two novel mercaptobenzimidazole derivative Schiff bases and their in vitro antioxidant and enzyme inhibitory effects
A Aras - Journal of the Indian Chemical Society, 2022 - Elsevier
Abstract In this study, 5-(2-hydroxy-4-methoxybenzylidenamino)-2-mercaptobenzimidazole
and 5-(4-hydroxy-3-methoxybenzylidenamino)-2-mercaptobenzimidazole Schiff base …
and 5-(4-hydroxy-3-methoxybenzylidenamino)-2-mercaptobenzimidazole Schiff base …
Comprehensive LC‐MS/MS phenolic profiling of Arum elongatum plant and bioaccessibility of phenolics in their infusions
Arum elongatum has various bioactive compounds including phenolic acids and flavonoids
that may have beneficial effects on human health. The main objectives of this study were to …
that may have beneficial effects on human health. The main objectives of this study were to …