CC chemokines, a subfamily of 27 chemotactic cytokines, are a component of intercellular
communication, which is crucial for the functioning of the tumor microenvironment. Although …

Cancer cell migration and invasion are integral components of metastatic disease, which is
the major cause of death in cancer patients. Cancer cells can disseminate and migrate via …

The roles of tumor-associated macrophages (TAMs) and circulating monocytes in human
cancer are poorly understood. Here, we show that monocyte subpopulation distribution and …

Tumor cells exist in close proximity with non-malignant cells. Extensive and multilayered
crosstalk between tumor cells and stromal cells tailors the tumor microenvironment (TME) to …

Macrophages constitute a major immune component in tumor tissues, but how these cells
adapt to and survive in the nutrient-depleted and lactic acid–induced acidic tumor …

Tumor-associated macrophages (TAMs) constitute a large population of glioblastoma and
facilitate tumor growth and invasion of tumor cells, but the underlying mechanism remains …

The accumulation of tumour-associated macrophages (TAMs) in the hypoxic tumour
microenvironment (TME) is associated with malignant progression in cancer. However, the …

Ligands targeting nucleic acid-sensing receptors activate the innate immune system and
play a critical role in antiviral and antitumoral therapy. However, ligand design for in situ …

Compelling evidence suggests that inflammatory components contribute to cancer
development. However, eosinophils, involved in several inflammatory diseases, were not …

Simple Summary Breast cancer is a major public health problem with a large impact on the
life of patients and their families. It is a highly curable disease when detected early, and an …