Stress, stress hormones, and adult neurogenesis

TJ Schoenfeld, E Gould - Experimental neurology, 2012 - Elsevier
The dentate gyrus of the hippocampus continues to produce new neurons throughout
adulthood. Adult neurogenesis has been linked to hippocampal function, including learning …

Sex, hormones and neurogenesis in the hippocampus: hormonal modulation of neurogenesis and potential functional implications

LAM Galea, SR Wainwright, MM Roes… - Journal of …, 2013 - Wiley Online Library
The hippocampus is an area of the brain that undergoes dramatic plasticity in response to
experience and hormone exposure. The hippocampus retains the ability to produce new …

Daily exercise improves memory, stimulates hippocampal neurogenesis and modulates immune and neuroimmune cytokines in aging rats

RB Speisman, A Kumar, A Rani, TC Foster… - Brain, behavior, and …, 2013 - Elsevier
We tested whether daily exercise modulates immune and neuroimmune cytokines,
hippocampus-dependent behavior and hippocampal neurogenesis in aging male F344 rats …

Environmental enrichment restores neurogenesis and rapid acquisition in aged rats

RB Speisman, A Kumar, A Rani, JM Pastoriza… - Neurobiology of …, 2013 - Elsevier
Strategies combatting cognitive decline among the growing aging population are vital. We
tested whether environmental enrichment could reverse age-impaired rapid spatial search …

Chronic restraint stress in adolescence differentially influences hypothalamic‐pituitary‐adrenal axis function and adult hippocampal neurogenesis in male and female …

CK Barha, S Brummelte, SE Lieblich… - …, 2011 - Wiley Online Library
Previous studies have shown a relationship between adversity in adolescence and health
outcomes in adulthood in a sex‐specific manner. Adolescence is characterized by major …

Behavioral and structural adaptations to stress

HA Cameron, TJ Schoenfeld - Frontiers in neuroendocrinology, 2018 - Elsevier
Unpredictable aversive experiences, or stressors, lead to changes in depression-and
anxiety-related behavior and to changes in hippocampal structure including decreases in …

Hippocampal neurogenesis levels predict WATERMAZE search strategies in the aging brain

J Gil-Mohapel, PS Brocardo, W Choquette, R Gothard… - PLoS …, 2013 - journals.plos.org
The hippocampus plays a crucial role in the formation of spatial memories, and it is thought
that adult hippocampal neurogenesis may participate in this form of learning. To better …

Progesterone treatment normalizes the levels of cell proliferation and cell death in the dentate gyrus of the hippocampus after traumatic brain injury

CK Barha, T Ishrat, JR Epp, LAM Galea, DG Stein - Experimental neurology, 2011 - Elsevier
Traumatic brain injury (TBI) increases cell death in the hippocampus and impairs
hippocampus-dependent cognition. The hippocampus is also the site of ongoing …

Sex differences in neurogenesis and activation of new neurons in response to spatial learning and memory

C Chow, JR Epp, SE Lieblich, CK Barha… - …, 2013 - Elsevier
Adult hippocampal neurogenesis is often associated with hippocampus-dependent learning
and memory. Throughout a new neuron's development, it is differentially sensitive to factors …

Hippocampus-dependent learning influences hippocampal neurogenesis

JR Epp, C Chow, LAM Galea - Frontiers in neuroscience, 2013 - frontiersin.org
The structure of the mammalian hippocampus continues to be modified throughout life by
continuous addition of neurons in the dentate gyrus. Although the existence of adult …