Platinating agents, including cisplatin, carboplatin, and oxaliplatin, have been used clinically
for nearly 30years as part of the treatment of many types of cancers, including head and …

Chemotherapy‐induced peripheral neuropathy (CIPN) is a common, dose‐limiting side
effect of many chemotherapeutic agents. Although many therapies have been investigated …

Erythropoietin mediates an evolutionarily conserved, ancient immune response that limits
damage to the heart, the nervous system and other tissues following injury. New evidence …

Erythropoietin (EPO), originally discovered as hematopoietic growth factor, has direct effects
on cells of the nervous system that make it a highly attractive candidate drug for …

Peripheral neurotoxicity is a frequent dose‐limiting side effect of the chemotherapeutic agent
cisplatin. This study was conducted to investigate the preventive effect of oxytocin (OT) on …

Paclitaxel causes a sensory polyneuropathy with characteristic features of distal axonal
degeneration. Although the exact mechanisms underlying distal axonal degeneration are …

In the present study, the beneficial effect of hesperidin (HP), a citrus flavonoid, on cisplatin
(CP)-induced neurotoxicity was investigated. A total of 28 rats were equally divided into four …

Purpose: Antineoplastic drugs, such as cisplatin (CDDP), are severely neurotoxic, causing
disabling peripheral neuropathies with clinical signs known as chemotherapy-induced …

PURPOSE: To evaluate the central nervous system toxicity of cisplatin and neuroprotective
effect of selenium. METHODS: Twenty-one male Wistar albino rats were divided into three …

Cisplatin is an anticancer drug and it has neurotoxic effects. On the other hand, the
neuroprotective effect of selenium was observed in previous studies. However, the effect of …