Proteoglycans: systems-level insight into their expression in healthy and diseased placentas

O Oravecz, A Balogh, R Romero, Y Xu… - International Journal of …, 2022 - mdpi.com
Proteoglycan macromolecules play key roles in several physiological processes (eg,
adhesion, proliferation, migration, invasion, angiogenesis, and apoptosis), all of which are …

Review of alterations in perlecan-associated vascular risk factors in dementia

AL Trout, I Rutkai, IJ Biose, GJ Bix - International Journal of Molecular …, 2020 - mdpi.com
Perlecan is a heparan sulfate proteoglycan protein in the extracellular matrix that structurally
and biochemically supports the cerebrovasculature by dynamically responding to changes …

Dysregulation of placental functions and immune pathways in complete hydatidiform moles

JR King, ML Wilson, S Hetey, P Kiraly… - International Journal of …, 2019 - mdpi.com
Gene expression studies of molar pregnancy have been limited to a small number of
candidate loci. We analyzed high-dimensional RNA and protein data to characterize …

[PDF][PDF] Cathepsin D elevates the fibrocalcific activity in human aortic valve cells through the ERK1/2-Sox9 pathway

X Meng, Q Yao, B Nedumaran, Y Zhai, L Ao… - Frontiers in …, 2024 - frontiersin.org
Background: Human Aortic valve interstitial cells (AVICs) from calcific aortic valve disease
(CAVD)-affected valves exhibit elevated fibrocalcific activity although the underlying …

Maternal serum perlecan levels in women with preeclampsia

M Akbas, FM Koyuncu, B Artunc-Ulkumen… - Hypertension in …, 2020 - Taylor & Francis
Objective: Perlecan is an extracellular matrix proteoglycan suggested to maintain
endothelial functions. We aimed to measure maternal serum perlecan levels in different …

蛋白聚糖在胎盘源性疾病中的生物标志物作用.

李海英, 吴涛, 乔宠 - Journal of China Medical University, 2023 - search.ebscohost.com
摘要胎盘功能障碍可导致早期流产或子痫前期和宫内生长受限等胎盘源性疾病,
特殊的病原体(如感染恶性疟原虫) 侵袭胎盘后也会导致胎儿和(或) 母体健康受损 …

[PDF][PDF] Maternal serum perlecan and ischemia modified albumin levels as biomarkers of preeclampsia severity

ER Mokhtar, FA Abd El-Hakam, EE Ebriheem… - Egypt J …, 2022 - ejimmunology.org
Preeclampsia (PE) is a pregnancy disorder characterized by hypertension and end-organ
damage. Reliable biochemical markers for diagnosis and prediction of PE severity can …

[HTML][HTML] Proteomic identification of Placental Protein 1 (PP1), PP8, and PP22 and characterization of their placental expression in healthy pregnancies and in …

S Szabo, K Karaszi, R Romero, E Toth, A Szilagyi… - Placenta, 2020 - Elsevier
Abstract Introduction Placental Protein 1 (PP1), PP8, and PP22 were isolated from the
placenta. Herein, we aimed to identify PP1, PP8, and PP22 proteins and their placental and …

Evaluation of serum perlecan levels in pregnancy with mild and severe preeclampsia

U Erkayıran, A Tok, S Karaküçük… - Journal of Health …, 2021 - dergipark.org.tr
Aim: To determine the levels of perlecan, which contributes to autophagy inhibition and
angiogenesis, in severe and mild preeclamptic women. Material and Method: A total of 89 …

[引用][C] Evaluation of serum perlecan levels in pregnancy with mild and severe preeclampsia

U ERKAYIRAN, A Tok, S KARAKÜÇÜK… - Medicine Science, 2021