Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive subtype of
kidney cancer, with high mortality rates worldwide. The sonic hedgehog (SHH) molecular …

Quantitative reverse transcription polymerase chain reaction (qRT-PCR) in thyroid tumors
require accurate data normalization, however, there are no sufficient studies addressing the …

Colorectal cancer (CRC) is an emerging global problem with the rapid increase in its
incidence being associated with an unhealthy lifestyle. Epidemiological studies have shown …

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of RCC (70-80%). Yes-
associated protein 1 (YAP1) protein is a nuclear effector of the Hippo pathway and acts as a …

Cumulative studies have shown that RNA binding proteins (RBPs) play an important role in
numerous malignant tumors and are related to the occurrence and progression of tumors …

3D spheroids are built by heterogeneous cell types in different proliferative and metabolic
states and are enriched in cancer stem cells. The main aim of the study was to investigate …

In recent years, genome-wide RNA expression analysis has become a routine tool that
offers a great opportunity to study and understand the key role of genes that contribute to …

There is a host of evidence for the role of bioactive sphingolipids in cancer biology, and
dysregulated sphingolipid metabolism was observed in many malignant tumors. The aim of …

Clear cell renal cell carcinoma (ccRCC) is the most common and the most aggressive
histopathological subtype of kidney cancer, with patients exhibiting high mortality rates for …

Prediction of recurrence is a challenge for the development of adjuvant treatments in clear-
cell renal cell carcinoma (ccRCC). In these tumors, expression of long non-coding RNAs …